Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

NCT00029380 · View on ClinicalTrials.gov ↗

Study Summary

This study will develop a national cord blood bank for siblings of patients with hemoglobinopathies and thalassemia.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Busulfan
  • DRUG Mycophenolate Mofetil
  • DRUG Cyclosporine
  • DRUG Sangstat

Study Locations (15)

California

  • Children's Hospital Oakland — Oakland
  • Children's Hospital, Oakland — Oakland

Florida

  • Nemours Children's Clinic — Jacksonville
  • University of Miami Batchelor Children's Research Center — Miami

Texas

  • University of Texas Southwestern Medical Center - Dallas — Dallas
  • Texas Transplant Institute — San Antonio

District of Columbia

  • Children's National Medical Center — Washington D.C.

Illinois

  • Children's Memorial Hospital — Chicago

Louisiana

  • Louisiana State University Children's Medical Center — New Orleans

Michigan

  • University of Michigan — Ann Arbor

New Jersey

  • Hackensack University Medical Center — Hackensack

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 1999-01
Est. Completion 2006-08
Phase Phase 2

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00029380

The ClinicalTrials.gov registry entry for NCT00029380 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Heart, Lung, and Blood Institute (NHLBI), which has 381 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Hematopoietic Stem Cell Transplantation appearing as the primary indexed condition, and to 5 interventions — of which Cyclophosphamide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00029380 reports 15 study locations spanning 12 distinct geographic areas — top geographies include California, Florida, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00029380 about?

NCT00029380 is a clinical study titled "Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia". This study will develop a national cord blood bank for siblings of patients with hemoglobinopathies and thalassemia.

What is the current status of trial NCT00029380?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 1999-01. Estimated completion is 2006-08.

What conditions does trial NCT00029380 study?

This clinical trial studies the following conditions: Hematopoietic Stem Cell Transplantation, Hematologic Diseases, Anemia, Sickle Cell, Beta-Thalassemia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00029380?

The interventions under investigation include: Cyclophosphamide (DRUG), Busulfan (DRUG), Mycophenolate Mofetil (DRUG), Cyclosporine (DRUG), Sangstat (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00029380?

This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 381 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00029380 being conducted?

This trial has 15 study locations across California, District of Columbia, Florida, Illinois, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial