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NCT00001880 · ClinicalTrials.gov registry record · Phase 2

Stem Cell Transplantation for Metastatic Solid Tumors

A Phase 2 study, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

Terminated
Registry status
Phase 2
Development phase
42
Enrollment target

NCT00001880 is a Phase 2 study that was terminated before completion, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 42 participants.

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The verdict

NCT00001880, a Phase 2 study, was terminated before completion, sponsored by National Heart, Lung, and Blood Institute (NHLBI).

TERMINATED
Registry status
Phase 2
Development phase
42 participants
Enrollment target

Study Summary

The goal of this research study is to identify other types of cancer (malignant neoplasms) that may be treatable with stem cell transplantation (allogenic peripheral blood stem cell transplantation. Patients with a variety of different types of cancerous tumors that have spread (metastasized) and whose conditions have not improved with stand therapy, will be eligible to participate. Those patients selected to participate in the study will undergo a procedure known as a "mini-transplant". The mini-transplant is a transplantation of stem-cells collected from a sibling (brother or sister) of the patient. Unlike traditional bone marrow transplants, the mini-transplant does not require intense chemotherapy or radiation therapy. Because of this, patients experience fewer and less severe side effects. This study is open to patients diagnosed with a variety of metastatic solid tumors including esophageal, gastric (stomach), colon, rectal, liver tumors (hepatoma), cancer of the biliary system (cholangiocarcinoma), cancer of the pancreas, lung, breast, prostate, bone (sarcoma), adrenal basal cell, bladder, and adenocarcinomas of unk primary origin.

Interventions

  • DRUG methotrexate
  • DRUG Cyclosporin

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 1999-03-12
Est. Completion 2020-08-13
Phase Phase 2

What the Registry Record Tells You About NCT00001880

The ClinicalTrials.gov registry entry for NCT00001880 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Heart, Lung, and Blood Institute (NHLBI), which has 501 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which methotrexate is the first listed.

NCT00001880 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00001880 about?

NCT00001880 is a clinical study titled "Stem Cell Transplantation for Metastatic Solid Tumors". The goal of this research study is to identify other types of cancer (malignant neoplasms) that may be treatable with stem cell transplantation (allogenic peripheral blood stem cell transplantation. Patients with a variety of different types of cancerous tumors that have spread (metastasized) and w...

What is the current status of trial NCT00001880?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 1999-03-12. Estimated completion is 2020-08-13.

What interventions are being tested in trial NCT00001880?

The interventions under investigation include: methotrexate (DRUG), Cyclosporin (DRUG).

Who is sponsoring clinical trial NCT00001880?

This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.