Gilead Sciences

504 total trials 26 currently recruiting 346 completed

Gilead Sciences sponsors 504 registered US clinical trials on ClinicalTrials.gov, 26 of them currently recruiting, and 346 completed. 164 of these trials are in Phase 3-4 (later-stage) and 317 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV-1-infection, with 20 trials.

Trial Pipeline

504 total, page 1 of 11

RECRUITING Phase 2

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or Chemotherapy in Adults With Metastatic Gastric, Gastroesophageal Junction (GEJ), and Esophageal Adenocarcinomas

NCT07546812

RECRUITING Phase 2

A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1

NCT07645287

RECRUITING Phase 1

Study of GS-2426 in Participants With Advanced Solid Tumors

NCT07601243

RECRUITING Phase 2

Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer

NCT07527858

RECRUITING

Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention

NCT07473778

RECRUITING Phase 1

Study of GS-5319 in Adults With Solid Tumors

NCT07128303

RECRUITING Phase 1

Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Newborns Exposed to HIV

NCT07055451

RECRUITING Phase 1

Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus

NCT07096193

RECRUITING Phase 3

Study of Lenacapavir as a Once-Yearly Injection for HIV Pre-exposure Prophylaxis (PrEP)

NCT07047716

RECRUITING Phase 1

Study of GS-3242 in Participants With HIV-1; Substudy-05

NCT07001319

RECRUITING Phase 1

Study of GS-0151 in Participants With Rheumatoid Arthritis

NCT06902519

RECRUITING Phase 1

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

NCT06926920

RECRUITING Phase 3

Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

NCT06801834

RECRUITING Phase 2

Evaluation of Long-Acting Lenacapavir for the Treatment of HIV-1 in Treatment-experienced Adolescents and Children

NCT06749054

RECRUITING Phase 2

Study of Bictegravir/Lenacapavir in Children and Adolescents With HIV-1

NCT06532656

RECRUITING Phase 1

Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)

NCT06562907

RECRUITING Phase 1

Study of GS-2121 Given Alone or in Combination in Adults With Advanced Solid Tumors

NCT06532565

RECRUITING Phase 1

Study of GS-0201 Alone and in Combination in Participants With Advanced Solid Tumors

NCT06167317

RECRUITING Phase 2

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

NCT06029972

RECRUITING Phase 3

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

NCT06051617

RECRUITING Phase 2

Study of Novel Treatment Combinations in Patients With Lung Cancer

NCT05633667

RECRUITING Phase 3

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

NCT05633654

RECRUITING Phase 1

Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

NCT05007782

RECRUITING Phase 1

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

NCT04617522

RECRUITING Phase 2

Study of Sacituzumab Govitecan in Participants With Urothelial Cancer That Cannot Be Removed or Has Spread

NCT03547973

RECRUITING Phase 2

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

NCT02932150

ACTIVE NOT RECRUITING Phase 2

Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01

NCT06727565

ACTIVE NOT RECRUITING Phase 2

Study of Oral Weekly GS-1720 and GS-4182 Compared With Biktarvy in People With HIV-1 Who Have Not Been Treated

NCT06613685

ACTIVE NOT RECRUITING Phase 3

Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People With HIV-1

NCT06630286

ACTIVE NOT RECRUITING Phase 3

Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Standard of Care in Virologically Suppressed People With HIV-1

NCT06630299

ACTIVE NOT RECRUITING Phase 3

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Participants With Endometrial Cancer After Platinum-Based Chemotherapy and Immunotherapy (ASCENT-GYN-01/GOG-3104/ENGOT-en26)

NCT06486441

ACTIVE NOT RECRUITING Phase 2

Study of Oral Weekly GS-1720 and GS-4182 Versus Biktarvy in People With HIV-1 Who Are Virologically Suppressed

NCT06544733

ACTIVE NOT RECRUITING Phase 2

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

NCT06290934

ACTIVE NOT RECRUITING Phase 3

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With Biktarvy

NCT06333808

ACTIVE NOT RECRUITING Phase 2

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) for Prevention of HIV in People Who Inject Drugs (HPTN 103)

NCT06101342

ACTIVE NOT RECRUITING Phase 2

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)

NCT06101329

ACTIVE NOT RECRUITING Phase 1

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

NCT06082960

ACTIVE NOT RECRUITING Phase 1

Study of GS-0272 in Participants With Rheumatoid Arthritis

NCT06031415

ACTIVE NOT RECRUITING Phase 3

Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC)

NCT06060665

ACTIVE NOT RECRUITING Phase 2

A Study of Teropavimab and Zinlirvimab in Combination With Capsid Inhibitor Lenacapavir in Virologically Suppressed Adults With HIV-1 Infection

NCT05729568

ACTIVE NOT RECRUITING Phase 1

Study of GS-4528 in Adults With Solid Tumors

NCT05840224

ACTIVE NOT RECRUITING Phase 3

Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy

NCT05840211

ACTIVE NOT RECRUITING Phase 2

Study With Various Immunotherapy Treatments in Participants With Lung Cancer

NCT05676931

ACTIVE NOT RECRUITING Phase 3

Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer

NCT05502237

ACTIVE NOT RECRUITING Phase 2

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen

NCT05502341

ACTIVE NOT RECRUITING Phase 3

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

NCT05382286

ACTIVE NOT RECRUITING Phase 3

Study of Sacituzumab Govitecan-hziy Versus Treatment of Physician's Choice in Patients With Previously Untreated Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

NCT05382299

ACTIVE NOT RECRUITING Phase 2

Study of Sacituzumab Govitecan Combinations in First-line Treatment of Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC)

NCT05186974

ACTIVE NOT RECRUITING Phase 3

Study of Sacituzumab Govitecan (SG) Versus Docetaxel in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

NCT05089734

ACTIVE NOT RECRUITING Phase 2

Study Evaluating the Safety and Efficacy of Islatravir in Combination With Lenacapavir in Virologically Suppressed People With HIV

NCT05052996

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What the Pipeline for Gilead Sciences Shows

According to the ClinicalTrials.gov registry, Gilead Sciences is linked to 504 US clinical trials across every stage of research activity. Of those, 26 studies are currently recruiting, about 5% of the sponsor's indexed portfolio, and 346 are already marked complete, representing roughly 69% of the total.

The phase mix for Gilead Sciences reports 164 late-stage studies (Phase 3 and Phase 4 combined) and 317 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Gilead Sciences is HIV-1-infection with 20 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.