Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

ACTIVE NOT RECRUITING Phase 2

Study With Various Immunotherapy Treatments in Participants With Lung Cancer

NCT05676931 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the objective response rate (ORR) of immunotherapy-based combination therapy and to assess the safety and tolerability of immunotherapy-based combination therapy.

Interventions

  • DRUG Docetaxel
  • DRUG Zimberelimab
  • DRUG Quemliclustat
  • DRUG Domvanalimab
  • DRUG Platinum-Based Doublet

Study Locations (20)

Other

  • CHU Bordeaux Centre Francois Magendie Hôpital du Haut Lévèque — Bordeaux
  • Hospices Civils de Lyon Centre Hospitalier Lyon Sud — Lyon
  • Institut De Cancerologie Strasbourg Europe ICANS — Strasboug
  • Hopital FOCH — Suresnes
  • LTD High Technology Hospital Medcenter — Batumi
  • Caucasus Medical Center — Tbilisi
  • Israel Georgian Medical Research Clinic Healthycore — Tbilisi

Florida

  • Memorial Cancer Institute at Memorial Regional Hospital — Hollywood
  • Hematology Oncology Associates Of The Treasure Coast — Port Saint Lucie
  • Florida Cancer Specialists (Administration and Drug Shipment) — The Villages

Alabama

  • University of Alabama at Birmingham (UAB) — Birmingham

California

  • University of California San Diego (UCSD) — La Jolla

Illinois

  • Northwestern Memorial Hospital — Chicago

Louisiana

  • Ochsner Clinic Foundation — Jefferson

Michigan

  • Henry Ford Hospital — Detroit

Washington

  • Medical Oncology Associated, PS (dba Summit Cancer Centers) — Spokane

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2023-02-21
Est. Completion 2027-12
Phase Phase 2

Sponsor

Gilead Sciences

190 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05676931

The ClinicalTrials.gov registry entry for NCT05676931 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 400 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 190 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Advanced Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 5 interventions — of which Docetaxel is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05676931 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Other, Florida, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05676931 about?

NCT05676931 is a clinical study titled "Study With Various Immunotherapy Treatments in Participants With Lung Cancer". The purpose of this study is to assess the objective response rate (ORR) of immunotherapy-based combination therapy and to assess the safety and tolerability of immunotherapy-based combination therapy.

What is the current status of trial NCT05676931?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 400 participants. The study started on 2023-02-21. Estimated completion is 2027-12.

What conditions does trial NCT05676931 study?

This clinical trial studies the following conditions: Advanced Non-Small Cell Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05676931?

The interventions under investigation include: Docetaxel (DRUG), Zimberelimab (DRUG), Quemliclustat (DRUG), Domvanalimab (DRUG), Platinum-Based Doublet (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05676931?

This trial is sponsored by Gilead Sciences, which has 190 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05676931 being conducted?

This trial has 20 study locations across Alabama, California, Florida, Illinois, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial