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RECRUITING Phase 2

Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection

NCT02932150 · View on ClinicalTrials.gov ↗

Study Summary

The goals of this clinical study are to compare the effectiveness, safety and tolerability of study drug, tenofovir alafenamide (TAF), versus placebo in teens and children with CHB and to learn more about the dosing levels in children.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG TAF

Study Locations (20)

Texas

  • Children's Medical Center — Dallas
  • Cook Children's Medical Center — Fort Worth
  • Texas Children's Hospital - Main Hospital — Houston
  • American Research Corporation at Texas Liver Institute — San Antonio

California

  • Children's Hospital of Los Angeles — Los Angeles
  • Rady Childrens Hospital — San Diego
  • University of California, San Francisco (UCSF) — San Francisco

Florida

  • University of Miami/Schiff Center for Liver Diseases — Miami
  • AdventHealth Medical Group — Orlando

Ohio

  • Cincinnati Children's Hospital Medical Center — Cincinnati
  • Nationwide Children's Hospital — Columbus

Colorado

  • Children's Hospital Colorado — Aurora

Georgia

  • Children's Healthcare of Atlanta — Atlanta

Indiana

  • Indiana University School of Medicine — Indianapolis

Maryland

  • Johns Hopkins University — Baltimore

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2016-11
Est. Completion 2029-10
Phase Phase 2

Sponsor

Gilead Sciences

190 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02932150

The ClinicalTrials.gov registry entry for NCT02932150 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 190 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Chronic Hepatitis B appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02932150 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Texas, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02932150 about?

NCT02932150 is a clinical study titled "Study of Tenofovir Alafenamide (TAF) in Children and Teen Participants With Chronic Hepatitis B Virus Infection". The goals of this clinical study are to compare the effectiveness, safety and tolerability of study drug, tenofovir alafenamide (TAF), versus placebo in teens and children with CHB and to learn more about the dosing levels in children.

What is the current status of trial NCT02932150?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 150 participants. The study started on 2016-11. Estimated completion is 2029-10.

What conditions does trial NCT02932150 study?

This clinical trial studies the following conditions: Chronic Hepatitis B. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02932150?

The interventions under investigation include: Placebo (DRUG), TAF (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02932150?

This trial is sponsored by Gilead Sciences, which has 190 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02932150 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial