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Hepatitis C, Chronic
Open-data reference.
27 US clinical trials · 1 currently recruiting
Active & Recent Trials
Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy
Catherine Anne Chappell
NCT05140941
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03520660
A Study on the Correlation Between Interleukin 28B Genotypes With Clinical and Demographic Characteristics in Treatment-Naïve and Treatment-Experienced Patients With Chronic Hepatitis C
Hoffmann-La Roche
NCT01675427
A Safety and Effectiveness Study of Telaprevir in Chronic, Genotype 1, Hepatitis C Patients That Failed Previous Standard Treatment
Tibotec BVBA
NCT00703118
A Gilead Sequence Registry of Subjects Who Did Not Achieve Sustained Virologic Response
Gilead Sciences
NCT01457768
A Study of Danoprevir Boosted With Low Dose Ritonavir in Combination With Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C Virus Infection
Hoffmann-La Roche
NCT01220947
A Study of RO5024048 in Combination With Pegasys and Copegus in Treatment-Naive Patients With Chronic Hepatitis C, Genotype 1 or 4
Hoffmann-La Roche
NCT00869661
GS-5885 Alone or in Combination With GS-9451 With Peginterferon Alfa 2a and Ribavirin in Treatment Chronic Genotype 1 Hepatitis C Virus
Gilead Sciences
NCT01356160
Dose Ranging of GSK2336805 in Combination Therapy
GlaxoSmithKline
NCT01648140
A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV
Atea Pharmaceuticals
NCT05904470
Safety Study of Regimens of Sofosbuvir, GS-0938, and Ribavirin in Patients With Chronic Hepatitis C Infection
Gilead Sciences
NCT01435044
A Study of Combination Therapy With PEGASYS (Pegylated Interferon Alfa-2a (40KD)) and Copegus (Ribavirin) in Patients With Chronic Hepatitis C Genotype 2 or 3 Who Do Not Achieve a Rapid Viral Response
Hoffmann-La Roche
NCT00623428
A Caspase Inhibitor in Chronic Hepatitis C (HCV) Patients
Conatus Pharmaceuticals
NCT00088140
A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With COPEGUS (Ribavirin) in Interferon-Naive Patients With Chronic Hepatitis C Infection (CHC).
Hoffmann-La Roche
NCT00077649
PHOENIX Study - A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) and COPEGUS (Ribavirin) Administered After Liver Transplantation for Hepatitis C.
Hoffmann-La Roche
NCT00087633
ANNAPURNA: A Study of The Combination of RO5466731, RO5190591, Ritonavir and Copegus (Ribavirin) With or Without RO5024048 in Patients With Chronic Hepatitis C Who Are Either Treatment-Naïve or Have Previously Experienced a Null Response to Interferon-Based Treatment
Hoffmann-La Roche
NCT01628094
Anticipated and Perceived Benefits Following Hepatitis C Treatment
University of North Carolina, Chapel Hill
NCT03000023
Safety, Antiviral Activity and PK of MRD of BI 201335 in Chronic Hepatitis C Patients Both Treatment Naive and -Experienced
Boehringer Ingelheim
NCT00793793
Viral Kinetics and Liver Gene Expression in Response to Ribavirin and Peginterferon Therapy of Chronic Hepatitis C
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00718172
Linkage to Care for Persons with Hep C Infection
Carilion Clinic
NCT05397067
SB497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Thrombocytopenia Due To Hepatitis C
GlaxoSmithKline
NCT00110799
A Study of Peginterferon Alfa-2a (Pegasys) and Ribavirin (Copegus) Combination Therapy in Participants With Chronic Hepatitis C (CHC) and Various Degrees of Renal Impairment
Hoffmann-La Roche
NCT02864199
Study of PEG-rIL-29 (or PEG-IFN Lambda) in Subjects With Chronic Hepatitis C Virus Infection
ZymoGenetics
NCT00565539
Intra-Individual Reproducibility of the Non-Invasive Assessment of the Portal Circulation
HepQuant
NCT01579162
IdB 1016 Treatment for Hepatitis C Disease
National Center for Complementary and Integrative Health (NCCIH)
NCT00055445
A Study of Ritonavir-Boosted Danoprevir and RO5024048 in Different Combinations in Null Responder or Treatment-Naïve Patients With Chronic Hepatitis C and Compensated Cirrhosis
Hoffmann-La Roche
NCT01483742
New Treatment Response in People With and Without Cirrhosis From Chronic Hepatitis C
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01888900
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 4 |
| Phase 2 | 11 |
| Phase 3 | 2 |
| Phase 4 | 6 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hepatitis C, Chronic Trial Landscape
ClinicalTrials.gov lists 27 US studies indexed under Hepatitis C, Chronic, and 1 of those are currently open to recruitment — roughly 4% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Hepatitis C, Chronic shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Hepatitis C, Chronic is led by Hoffmann-La Roche with 9 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hepatitis C, Chronic?
PlainTrial tracks 27 US clinical trials for Hepatitis C, Chronic, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hepatitis C, Chronic?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.