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Acquired Immunodeficiency Syndrome clinical trials
Every US clinical trial registered for Acquired Immunodeficiency Syndrome — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
18 US clinical trials · 1 currently recruiting
The research picture
Acquired Immunodeficiency Syndrome has 18 registered US clinical trials, 1 of them open to new participants right now — about 6% of the total.
- 1
- recruiting participants now
- 6%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Gilead Sciences
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus
M.D. Anderson Cancer Center
NCT02479698
Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and VRC07-523LS in HIV-1-Infected Adults
Boris Juelg, MD PhD
NCT04983030
HIV Prevention Intervention for Couples
National Development and Research Institutes
NCT00325585
Multidisciplinary Inpatient Palliative Care Intervention
Kaiser Permanente
NCT00325611
Managerial Database II
University of North Carolina, Chapel Hill
NCT01322217
Study to Evaluate Switching From Regimens Consisting of a Ritonavir-boosted Protease Inhibitor Plus Emtricitabine/Tenofovir Fixed-Dose Combination to the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir DF Single-Tablet Regimen in Virologically Suppressed, HIV-1 Infected Patients
Gilead Sciences
NCT01475838
Medications for Chronic HIV: Education and Collaboration
Boston University
NCT01038076
Safety and Efficacy of Cobicistat-boosted Darunavir in HIV Infected Adults
Gilead Sciences
NCT01440569
HIV, Buprenorphine, and the Criminal Justice System (STRIDE2)
Yale University
NCT03583138
Thalidomide to Treat Oral Lesions in HIV-Infected Patients
National Institute of Dental and Craniofacial Research (NIDCR)
NCT00001524
Cobicistat-containing Highly Active Antiretroviral Regimens in HIV-1 Infected Patients With Mild to Moderate Renal Impairment
Gilead Sciences
NCT01363011
Efficacy of Tenofovir Alafenamide Versus Placebo Added to a Failing Regimen Followed by Treatment With Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Plus Atazanavir in HIV-1 Positive, Antiretroviral Treatment-Experienced Adults
Gilead Sciences
NCT01967940
Twins Study of Gene Therapy for HIV Infection
National Human Genome Research Institute (NHGRI)
NCT00001535
Mesalamine to Reduce T Cell Activation in HIV Infection
University of California, San Francis
NCT01090102
Phase I Protocol for the Evaluation of the Safety and Immunogenicity of Vaccination With Synthetic HIV Envelope Peptides in Patients With Early Human Immunodeficiency Virus Infection
National Cancer Institute (NCI)
NCT00001386
Subcutaneously Administered Interleukin-12 Therapy in HIV-Infected Patients With Disseminated Mycobacterium Avium Complex Infection
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001763
Efficacy of Elevated CD4 Counts on CMV Retinitis
National Eye Institute (NEI)
NCT00091884
Voriconazole vs. Amphotericin B in the Treatment of Invasive Aspergillosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001646
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 3 |
| Phase 3 | 5 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Acquired Immunodeficiency Syndrome Trial Landscape
ClinicalTrials.gov lists 18 US studies indexed under Acquired Immunodeficiency Syndrome, and 1 of those are currently open to recruitment — roughly 6% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Acquired Immunodeficiency Syndrome shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Acquired Immunodeficiency Syndrome is led by Gilead Sciences with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 18 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Acquired Immunodeficiency Syndrome?
PlainTrial tracks 18 US clinical trials for Acquired Immunodeficiency Syndrome, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Acquired Immunodeficiency Syndrome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.