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RECRUITING Phase 1

A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer

NCT06926920 · View on ClinicalTrials.gov ↗

Study Summary

The goal of this clinical study is to learn more about the study drug sacituzumab govitecan-hziy (SG) given at an alternative dose and schedule, in participants with triple-negative breast cancer (TNBC). The primary objectives of this study are to assess the safety and tolerability of SG given at alternate dose and schedule, to assess the effect on objective response rate (ORR) and progression-free survival (PFS).

Interventions

  • DRUG Sacituzumab Govitecan-hziy (SG)

Study Locations (16)

Other

  • Seoul National University Hospital — Seoul
  • Severance Hospital, Yonsei University Health System — Seoul
  • Asan Medical Center — Seoul
  • Samsung Medical Center — Seoul

Tennessee

  • West Cancer Centre — Germantown
  • SCRI Oncology Partners — Nashville
  • Tennessee Oncology, PLLC — Nashville

Queensland

  • Sunshine Coast University Private Hospital — Birtinya
  • John Flynn Private Hospital — Tugun

California

  • Los Angeles Cancer Network (LACN) - Good Sam — Los Angeles

Georgia

  • Winship Cancer Institute - Emory University — Atlanta

Kansas

  • The University of Kansas Hospital — Westwood

Missouri

  • Siteman Cancer Center — St Louis

Texas

  • Texas Oncology - DFW — Dallas

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2025-04-30
Est. Completion 2028-06
Phase Phase 1

Sponsor

Gilead Sciences

190 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06926920

The ClinicalTrials.gov registry entry for NCT06926920 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 190 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Triple Negative Breast Cancer appearing as the primary indexed condition, and to 1 intervention — of which Sacituzumab Govitecan-hziy (SG) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06926920 reports 16 study locations spanning 10 distinct geographic areas — top geographies include Other, Tennessee, Queensland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06926920 about?

NCT06926920 is a clinical study titled "A Study of Sacituzumab Govitecan Given at an Alternative Dose and Schedule in Participants With Advanced Triple-Negative Breast Cancer". The goal of this clinical study is to learn more about the study drug sacituzumab govitecan-hziy (SG) given at an alternative dose and schedule, in participants with triple-negative breast cancer (TNBC). The primary objectives of this study are to assess the safety and tolerability of SG given at a...

What is the current status of trial NCT06926920?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2025-04-30. Estimated completion is 2028-06.

What conditions does trial NCT06926920 study?

This clinical trial studies the following conditions: Triple Negative Breast Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06926920?

The interventions under investigation include: Sacituzumab Govitecan-hziy (SG) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06926920?

This trial is sponsored by Gilead Sciences, which has 190 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06926920 being conducted?

This trial has 16 study locations across California, Georgia, Kansas, Missouri, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial