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ACTIVE NOT RECRUITING Phase 1

Study of GS-0272 in Participants With Rheumatoid Arthritis

NCT06031415 · View on ClinicalTrials.gov ↗

Study Summary

The goals of this clinical study are to learn more about the study drug, GS-0272, and its safety and tolerability following multiple doses in participants with rheumatoid arthritis (RA). The primary objectives of this study are to assess the safety and tolerability of multiple ascending doses of GS-0272 and to characterize the pharmacokinetics of GS-0272 following multiple doses of GS-0272, in participants with RA.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG GS-0272

Study Locations (20)

Other

  • ARENSIA Exploratory Medicine LLC — Tbilisi
  • IMSP Republican Clinical Hospital "Timofei Mosneaga", ARENSIA E.M. — Chisinau
  • Chungnam National University Hospital — Daejeon
  • Seoul National University Hospital — Seoul
  • Ajou University Hospital — Suwon
  • Cambridge Clinical Research Centre, Rheumatology Research Unit - E6, Addenbrookes Hospital — Cambridge

Texas

  • Precision Comprehensive Clinical Research Solutions — Colleyville
  • Accurate Clinical Research, Inc. — Houston
  • Precision Comprehensive Clinical Research Solutions — Irving
  • 1600 Republic Parkway — Mesquite

California

  • Arizona Arthritis & Rheumatology Associates P.C. — Glendale
  • Stanford School of Medicine, Division of Immunology & Rheumatology — Palo Alto
  • 1238 E. Arrow Hwy — Upland

Florida

  • Clinical Research of West Florida, Inc. — Clearwater
  • Jacksonville Center for Clinical Research — Jacksonville

Illinois

  • Greater Chicago Specialty Physicians/ Clinical Investigation Specialists — Niles
  • Greater Chicago Specialty Physicians/Clinical Investigation Specialists, Inc. — Schaumburg

Pennsylvania

  • Altoona Center for Clinical Research — Duncansville
  • PA Regional Center for Arthritis and Osteoporosis Research — Wyomissing

Oregon

  • Summit Headlands LLC — Portland

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2023-09-28
Est. Completion 2026-03
Phase Phase 1

Sponsor

Gilead Sciences

190 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06031415

The ClinicalTrials.gov registry entry for NCT06031415 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 190 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06031415 reports 20 study locations spanning 7 distinct geographic areas — top geographies include Other, Texas, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06031415 about?

NCT06031415 is a clinical study titled "Study of GS-0272 in Participants With Rheumatoid Arthritis". The goals of this clinical study are to learn more about the study drug, GS-0272, and its safety and tolerability following multiple doses in participants with rheumatoid arthritis (RA). The primary objectives of this study are to assess the safety and tolerability of multiple ascending doses of GS...

What is the current status of trial NCT06031415?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 55 participants. The study started on 2023-09-28. Estimated completion is 2026-03.

What conditions does trial NCT06031415 study?

This clinical trial studies the following conditions: Rheumatoid Arthritis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06031415?

The interventions under investigation include: Placebo (DRUG), GS-0272 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06031415?

This trial is sponsored by Gilead Sciences, which has 190 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06031415 being conducted?

This trial has 20 study locations across California, Florida, Illinois, Oregon, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial