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NCT06562907 · ClinicalTrials.gov registry record · Phase 1
Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)
A Phase 1 study of Weight Management, sponsored by Gilead Sciences.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 134
- Enrollment target
- 3
- Study locations
NCT06562907: Recruiting Phase 1 study of Weight Management, sponsored by Gilead Sciences.
NCT06562907 is a Phase 1 study of Weight Management that is actively recruiting participants, run by Gilead Sciences. The registered enrollment target is 134 participants, below the 852-participant average among 8 other Weight Management trials with a reported enrollment target (84% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06562907, a Phase 1 study of Weight Management, is actively recruiting participants, sponsored by Gilead Sciences.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 134 participants
- Enrollment target
- 3
- Study locations
Study Summary
The goal of this clinical study is to learn more about the study drug, GS-4571, and how safe it is in 3 groups, i) Healthy participants, ii) Healthy non-diabetic obese participants, and iii) Non-obese participants with Type 2 Diabetes Mellitus (T2DM). The primary objectives of this study are: * To characterize the pharmacokinetics (PK) of GS-4571 following single and multiple ascending oral doses of GS-4571. * To evaluate the effect of concomitant food intake and (if conducted) a representative acid-reducing agent (proton pump inhibitor (PPI), omeprazole) on the PK of GS-4571. * To evaluate the safety and tolerability of single and multiple ascending oral doses of GS-4571.
Primary Outcome
AUCinf is defined as area under the concentration versus time curve extrapolated to infinite time.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Omeprazole
- DRUG GS-4571
Study Locations (3)
Florida
- Qps-Mra, Llc. - Miami
Texas
- ICON Early Phase Services, LLC - San Antonio
Utah
- ICON - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 134 participants |
| Start Date | 2024-08-28 |
| Est. Completion | 2026-07 |
| Phase | Phase 1 |
What NCT06562907 shows while recruiting
NCT06562907 is an interventional study that assigns participants to a tested intervention. The registered 134 participants enrollment target is mid-sized for trials with a published cap, below the 852-participant average among 8 other Weight Management trials with a reported enrollment target (84% lower).
The record links to 1 condition, with Weight Management appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT06562907 reports a single indexed study location in Florida, Texas, Utah.
Frequently Asked Questions
What is clinical trial NCT06562907 about?
NCT06562907 is a clinical study titled "Study of GS-4571 in Healthy Participants, Nondiabetic Obese Participants, and Nonobese Participants With Type 2 Diabetes Mellitus (T2DM)". The goal of this clinical study is to learn more about the study drug, GS-4571, and how safe it is in 3 groups, i) Healthy participants, ii) Healthy non-diabetic obese participants, and iii) Non-obese participants with Type 2 Diabetes Mellitus (T2DM). The primary objectives of this study are: * To...
What is the current status of trial NCT06562907?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 134 participants. The study started on 2024-08-28. Estimated completion is 2026-07.
What conditions does trial NCT06562907 study?
This clinical trial studies the following conditions: Weight Management.
What interventions are being tested in trial NCT06562907?
The interventions under investigation include: Placebo (DRUG), Omeprazole (DRUG), GS-4571 (DRUG).
Who is sponsoring clinical trial NCT06562907?
This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06562907 being conducted?
This trial has 3 study locations across Florida, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Weight Management
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06562907's enrollment target sits among peer trials
134 3rd of 8 higher than 6 of 8 other Weight Management trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Weight Management trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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