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NCT06119529 · ClinicalTrials.gov registry record · Phase 1

A Study of LY3872386 in Healthy Participants and Participants With Atopic Dermatitis

A Phase 1 study, sponsored by Eli Lilly and Company.

Terminated
Registry status
Phase 1
Development phase
18
Enrollment target

NCT06119529: Clinical Trial Phase 1 study, sponsored by Eli Lilly and Company.

NCT06119529 is a Phase 1 study that was terminated before completion, run by Eli Lilly and Company. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06119529, a Phase 1 study, was terminated before completion, sponsored by Eli Lilly and Company.

TERMINATED
Registry status
Phase 1
Development phase
18 participants
Enrollment target

Study Summary

The main purpose of this study is to evaluate the safety and tolerability of LY3872386 in healthy participants and participants with atopic dermatitis. The safety of prednisone is also evaluated in healthy participants. Blood tests will be performed to investigate how the body processes the LY3872386 following single and multiple dosing in healthy participants and participants with atopic dermatitis. Blood tests will also be performed to investigate how the body processes the prednisone in healthy participants. The study is conducted in three parts (part A, B and C). The study will last up to approximately 85, 183 and 44 days for parts A, B, and C, respectively.

Primary Outcome

A summary of SAEs and other non-serious adverse events (AEs), regardless of causality is located in the Reported Adverse Event module. Drug related TEAEs are any untoward medical occurrences that either occurs postdose or presents prior to dosing yet becomes more severe postdose, and in the opinion of the investigator is possibly related to study drug.

Interventions

  • DRUG Placebo
  • DRUG Prednisone
  • DRUG LY3872386

Trial Details

FieldValue
Enrollment Target 18 participants
Start Date 2023-11-01
Est. Completion 2024-04-08
Phase Phase 1
Eli Lilly and Company

1,341 total trials

Why NCT06119529 stopped before completion

NCT06119529 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT06119529 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06119529 about?

NCT06119529 is a clinical study titled "A Study of LY3872386 in Healthy Participants and Participants With Atopic Dermatitis". The main purpose of this study is to evaluate the safety and tolerability of LY3872386 in healthy participants and participants with atopic dermatitis. The safety of prednisone is also evaluated in healthy participants. Blood tests will be performed to investigate how the body processes the LY387238...

What is the current status of trial NCT06119529?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2023-11-01. Estimated completion is 2024-04-08.

What interventions are being tested in trial NCT06119529?

The interventions under investigation include: Placebo (DRUG), Prednisone (DRUG), LY3872386 (DRUG).

Who is sponsoring clinical trial NCT06119529?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06119529's enrollment target sits among peer trials

18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06119529, the US trial registry maintained by the National Library of Medicine. NCT06119529 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.