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A Study of LY2784544 in Participants With Myeloproliferative Neoplasms
NCT01594723 · View on ClinicalTrials.gov ↗
Study Summary
The primary purpose of this study is to measure the response rate in participants with the myeloproliferative neoplasms (MPNs), polycythemia vera (PV), essential thrombocythemia (ET), or myelofibrosis (MF) when treated with LY2784544, including those who have demonstrated an intolerance to, failure of primary response to, or have demonstrated disease progression while on ruxolitinib.
Conditions Studied
Interventions
- DRUG 120 mg LY2784544
Study Locations (20)
Tennessee
- Baptist Cancer Center — Memphis
- Sarah Cannon Cancer Center — Nashville
- Tennessee Oncology PLLC — Nashville
Florida
- Lakeland Regional Cancer Center — Lakeland
- Palm Beach Cancer Institue — West Palm Beach
New York
- Weill Cornell Medical College — New York
- Albert Einstein College of Medicine — The Bronx
Ohio
- Cleveland Clinic Foundation — Cleveland
- Mid Ohio Oncology Hematology — Columbus
Arkansas
- Highlands Oncology Group - Duplicate 2 — Rogers
California
- Providence St. Joseph's Medical Center — Burbank
Connecticut
- Norwalk Hospital — Norwalk
Illinois
- Ingalls Memorial Hospital — Harvey
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2012-05-22 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01594723
The ClinicalTrials.gov registry entry for NCT01594723 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Neoplasms, Hematologic appearing as the primary indexed condition, and to 1 intervention — of which 120 mg LY2784544 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01594723 reports 20 study locations spanning 15 distinct geographic areas — top geographies include Tennessee, Florida, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01594723 about?
NCT01594723 is a clinical study titled "A Study of LY2784544 in Participants With Myeloproliferative Neoplasms". The primary purpose of this study is to measure the response rate in participants with the myeloproliferative neoplasms (MPNs), polycythemia vera (PV), essential thrombocythemia (ET), or myelofibrosis (MF) when treated with LY2784544, including those who have demonstrated an intolerance to, failure ...
What is the current status of trial NCT01594723?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 110 participants. The study started on 2012-05-22. Estimated completion is 2026-12.
What conditions does trial NCT01594723 study?
This clinical trial studies the following conditions: Neoplasms, Hematologic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT01594723?
The interventions under investigation include: 120 mg LY2784544 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT01594723?
This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01594723 being conducted?
This trial has 20 study locations across Arkansas, California, Connecticut, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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