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NCT06085482 · ClinicalTrials.gov registry record · Phase 1

A Phase I Study of LY3502970 in Healthy Participants

A Phase 1 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
10
Enrollment target

NCT06085482: Completed Phase 1 study, sponsored by Eli Lilly and Company.

NCT06085482 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06085482, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
10 participants
Enrollment target

Study Summary

The main purpose of this study is to evaluate how much of the study drug (LY3502970) and the radioactive substance 14C incorporated LY3502970 gets into the bloodstream, how its broken down, and how long it takes the body to get rid of it. The study will last up to approximately 9 weeks for each participant.

Primary Outcome

Absolute bioavailability of LY3502970, expressed in percentage, was estimated using the AUC(0-∞) values from each individual participant based on IV dosed \[14C\]-LY3502970 compared to oral dosed LY3502970, using formula: \[AUC0-∞(oral) x Dose (IV) divided by AUC0-∞(IV) x Dose (oral)\] x100. The sampling time points from pre-oral dose through 186 hours post-IV dose were used to assess this outcome.

Interventions

  • DRUG LY3502970
  • DRUG [14C]-LY3502970

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2023-10-19
Est. Completion 2024-01-05
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What the finished NCT06085482 record still lists

NCT06085482 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 2 interventions - of which LY3502970 is the first listed.

NCT06085482 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06085482 about?

NCT06085482 is a clinical study titled "A Phase I Study of LY3502970 in Healthy Participants". The main purpose of this study is to evaluate how much of the study drug (LY3502970) and the radioactive substance 14C incorporated LY3502970 gets into the bloodstream, how its broken down, and how long it takes the body to get rid of it. The study will last up to approximately 9 weeks for each part...

What is the current status of trial NCT06085482?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2023-10-19. Estimated completion is 2024-01-05.

What interventions are being tested in trial NCT06085482?

The interventions under investigation include: LY3502970 (DRUG), [14C]-LY3502970 (DRUG).

Who is sponsoring clinical trial NCT06085482?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06085482's enrollment target sits among peer trials

10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06085482, the US trial registry maintained by the National Library of Medicine. NCT06085482 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.