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A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
NCT06124807 · View on ClinicalTrials.gov ↗
Study Summary
The main purpose of this study, performed under a master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safety with LY3305677 compared with placebo and in adult participants with obesity or overweight. The study will last about 62 weeks.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG LY3305677
Study Locations (20)
Florida
- Northeast Research Institute (NERI) — Fleming Island
- Suncoast Clinical Research, Inc. — New Port Richey
- Charter Research - Winter Park — Orlando
- Charter Research - Lady Lake — The Villages
Arizona
- The Institute for Liver Health II dba Arizona Clinical Trials - Mesa — Chandler
- Headlands Research - Scottsdale — Scottsdale
- The Institute for Liver Health II dba Arizona Liver Health-Tucson — Tucson
California
- Velocity Clinical Research, Huntington Park — Huntington Park
- Peninsula Research Associates — Rolling Hills Estates
- Diablo Clinical Research, Inc. — Walnut Creek
Illinois
- Great Lakes Clinical Trials - Andersonville — Chicago
- Great Lakes Clinical Trials - Ravenswood — Chicago
New York
- Dent Neurologic Institute — Amherst
- North Suffolk Neurology — Port Jefferson Station
Hawaii
- Pacific Diabetes & Endocrine Center — Honolulu
Kansas
- Cotton O'Neil Diabetes & Endocrinology — Topeka
Kentucky
- L-MARC Research Center — Louisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 179 participants |
| Start Date | 2023-11-17 |
| Est. Completion | 2025-07-09 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06124807
The ClinicalTrials.gov registry entry for NCT06124807 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 179 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06124807 reports 20 study locations spanning 11 distinct geographic areas — top geographies include Florida, Arizona, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06124807 about?
NCT06124807 is a clinical study titled "A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight". The main purpose of this study, performed under a master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safety with LY3305677 compared with placebo and in adult participants with obesity or overweight. The study will last about 62 weeks.
What is the current status of trial NCT06124807?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 179 participants. The study started on 2023-11-17. Estimated completion is 2025-07-09.
What conditions does trial NCT06124807 study?
This clinical trial studies the following conditions: Obesity, Overweight and Obesity. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06124807?
The interventions under investigation include: Placebo (DRUG), LY3305677 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06124807?
This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06124807 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Hawaii, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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