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NCT06584916 · ClinicalTrials.gov registry record · Phase 3

A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)

A Phase 3 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 3
Development phase
376
Enrollment target

NCT06584916 is a Phase 3 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 376 participants.

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The verdict

NCT06584916, a Phase 3 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 3
Development phase
376 participants
Enrollment target

Study Summary

The main purpose of this study is to evaluate the efficacy and safety of orforglipron on maintenance of body weight reduction in participants who previously completed treatment with injectable tirzepatide (Zepbound) or injectable semaglutide (Wegovy) in the SURMOUNT-5 trial (NCT05822830).

Interventions

  • DRUG Placebo
  • DRUG Orforglipron

Trial Details

FieldValue
Enrollment Target 376 participants
Start Date 2024-09-13
Est. Completion 2025-11-21
Phase Phase 3

Sponsor

Eli Lilly and Company

1,341 total trials

What the Registry Record Tells You About NCT06584916

The ClinicalTrials.gov registry entry for NCT06584916 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 376 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT06584916 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06584916 about?

NCT06584916 is a clinical study titled "A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)". The main purpose of this study is to evaluate the efficacy and safety of orforglipron on maintenance of body weight reduction in participants who previously completed treatment with injectable tirzepatide (Zepbound) or injectable semaglutide (Wegovy) in the SURMOUNT-5 trial (NCT05822830).

What is the current status of trial NCT06584916?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 376 participants. The study started on 2024-09-13. Estimated completion is 2025-11-21.

What interventions are being tested in trial NCT06584916?

The interventions under investigation include: Placebo (DRUG), Orforglipron (DRUG).

Who is sponsoring clinical trial NCT06584916?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.