Columbia University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Columbia University sits in the top decile of US sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count).

958 total trials 171 currently recruiting 597 completed early-phase tilt top decile by trial count

Columbia University: 958 sponsored US clinical trials, 171 recruiting.

Columbia University sponsors 958 registered US clinical trials on ClinicalTrials.gov, 171 of them currently recruiting, and 597 completed. 88 of these trials are in Phase 3-4 (later-stage) and 191 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 9 trials.

Top-decile sponsor footprint

Columbia University ranks in the top decile of sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 42/100

597 of 736 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

958 total, page 4 of 20

RECRUITING

Longitudinal Study of Neurogenetic Disorders

NCT03492060

RECRUITING NA

Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)

NCT03292601

RECRUITING

Genes and Environment in Multiple Sclerosis

NCT01353547

RECRUITING Phase 2

Surgery and Heated Intraperitoneal Chemotherapy for Adrenocortical Carcinoma

NCT03127774

RECRUITING NA

Project I Test: Implementing HIV Testing in Opioid Treatment Programs

NCT03135886

RECRUITING

Late Onset Alzheimer's Disease

NCT05010603

RECRUITING

Genetic Studies of Early-onset Dementia

NCT04906863

RECRUITING

Tissue Repository: CTCL Collection Protocol

NCT02840747

RECRUITING

Physical Activity and Cognitive Development in Children

NCT02542683

RECRUITING

Gastric Emptying in Neonates and Infants After Formula Feeding

NCT02665923

RECRUITING

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

NCT02602769

RECRUITING

Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.

NCT01998750

RECRUITING NA

Evaluation of Post-PACU Pain Management in Pediatric Surgery

NCT02352116

RECRUITING

The Natural History Study of Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE)

NCT01694953

RECRUITING

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

NCT01694940

RECRUITING

Allergy and Immunology Natural History Study

NCT05584488

RECRUITING

Pancreatic Cancer Genetics

NCT01102569

RECRUITING

Study on Basal Joint Arthritis Prospective

NCT01376024

RECRUITING

Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science

NCT00950118

RECRUITING

PANCREATIC DISEASE COHORT A Registry and Biospecimen Bank to Better Understand Pancreatic Disease

NCT01102556

RECRUITING

Natural History Study - Mitochondrial Disease

NCT01532791

ACTIVE NOT RECRUITING NA

The Sleep2BWell Trial

NCT06565104

ACTIVE NOT RECRUITING NA

Living Healthy for Moms RCT

NCT06666400

ACTIVE NOT RECRUITING NA

HPV Vaccine Reminders - SEARCH II Study

NCT06161831

ACTIVE NOT RECRUITING NA

Young Adults With Violent Behavior During Early Psychosis (Aim 2)

NCT05756855

ACTIVE NOT RECRUITING NA

Mother-infant Bonding During COVID-19

NCT04531618

ACTIVE NOT RECRUITING NA

Integrated Care and Treatment for Severe Infectious Diseases and Substance Use Disorders Among Hospitalized Patients

NCT05688423

ACTIVE NOT RECRUITING NA

Implementing a Home Blood Pressure Monitoring Program in Primary Care

NCT05885997

ACTIVE NOT RECRUITING

TeleMAb Retrospective Cohort Study

NCT07405294

ACTIVE NOT RECRUITING Phase 2

Effect of Rapamycin in Ovarian Aging

NCT05836025

ACTIVE NOT RECRUITING NA

CT for Personalized Mechanical Ventilation

NCT05977153

ACTIVE NOT RECRUITING Phase 2

Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study

NCT05695027

ACTIVE NOT RECRUITING NA

Trial of Crisis Intervention Team (CIT) Mental Health Training for Police Officers

NCT05606289

ACTIVE NOT RECRUITING

Alpha-1 Antitrypsin Disease Cohort: Longitudinal Biomarker Study of Disease

NCT05297812

ACTIVE NOT RECRUITING NA

CAMP Air: Efficacy and Cost-effectiveness in Urban Adolescents

NCT05091034

ACTIVE NOT RECRUITING

ARMOR-Household: Characterizing Transmission of COVID-19 in Households of SARS-CoV-2 Index Cases

NCT05467917

ACTIVE NOT RECRUITING NA

TREAT to Improve Cardiometabolic Health

NCT04465721

ACTIVE NOT RECRUITING

A Prospective Natural History Study in Uveal Melanoma

NCT04588662

ACTIVE NOT RECRUITING Phase 2

Metformin in Alzheimer's Dementia Prevention

NCT04098666

ACTIVE NOT RECRUITING Phase 2

Romosozumab/Denosumab Study for Premenopausal IOP

NCT04800367

ACTIVE NOT RECRUITING NA

Eating Behaviors in Shift Workers

NCT04468672

ACTIVE NOT RECRUITING

Genentech Validation Tool for Pulmonary Fibrosis

NCT04676594

ACTIVE NOT RECRUITING Phase 2

Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs)

NCT04375228

ACTIVE NOT RECRUITING NA

Integrated HIV Prevention and HCV Care for PWID

NCT03981445

ACTIVE NOT RECRUITING NA

Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT)

NCT04271709

ACTIVE NOT RECRUITING Early Phase 1

A Study of Combination Spartalizumab and Canakinumab in Patients With Localized Clear Cell Renal Cell Carcinoma

NCT04028245

ACTIVE NOT RECRUITING Phase 2

18F-DCFPyL Positron Emission Tomography (PET)/Computed Tomography (CT) in Men With Prostate Cancer

NCT03824275

ACTIVE NOT RECRUITING Phase 2

Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma

NCT03839498

ACTIVE NOT RECRUITING Phase 2

Prostate Cancer Monitoring Using [18F]DCFPyL and Blood Based Biomarkers

NCT03585114

ACTIVE NOT RECRUITING Phase 3

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial - Hemodynamics (CREST-H)

NCT03121209

← Previous Page 4 of 20 Next →

Phase Distribution

PhaseTrial count
Phase 1 86
Phase 2 105
Phase 3 23
Phase 4 65

What is open in the Columbia University pipeline

171 recruiting of 958 indexed (18% open); 597 completed (62%).

Phase mix: 88 late (III/IV) vs 191 early (I/II) (early-phase heavy).

Top condition: Obesity (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Columbia University: open-pipeline peers nationwide

Peers matched on 958 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Columbia UniversityUniversity of MinnesotaBrigham and Women's HospitalHoffmann-La RocheUniversity of California, Los AngelesKite, A Gilead CompanyMirum PharmaceuticalsWest Virginia UniversityHospital for Special Surgery, New York
Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 958 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Columbia University page

958 registered trials is a research-attention snapshot, not an endorsement of Columbia University or any single study.

  • 171 of Columbia University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Columbia University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Columbia University pipeline card: 958 registered trials from official public datasets.Report a data error.