Columbia University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Columbia University sits in the top decile of US sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count).

958 total trials 171 currently recruiting 597 completed early-phase tilt top decile by trial count

Columbia University: 958 sponsored US clinical trials, 171 recruiting.

Columbia University sponsors 958 registered US clinical trials on ClinicalTrials.gov, 171 of them currently recruiting, and 597 completed. 88 of these trials are in Phase 3-4 (later-stage) and 191 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 9 trials.

Top-decile sponsor footprint

Columbia University ranks in the top decile of sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 42/100

597 of 736 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

958 total, page 5 of 20

ACTIVE NOT RECRUITING

Comparison of the Breast Tumor Microenvironment

NCT03165487

ACTIVE NOT RECRUITING NA

Intraoperative Radiation Therapy (IORT) in DCIS

NCT03216421

ACTIVE NOT RECRUITING NA

Low GI Diet in Children and Adolescents With ALL

NCT03157323

ACTIVE NOT RECRUITING Phase 1

Treatment of TK2 Deficiency With Thymidine and Deoxycytidine

NCT03639701

ACTIVE NOT RECRUITING

Northern Manhattan Study of Metabolism and Mind

NCT02470260

ACTIVE NOT RECRUITING Phase 2

Stem Cell Transplant in Sickle Cell Disease and Thalassemia

NCT00408447

NOT YET RECRUITING Phase 1

Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau

NCT06600880

NOT YET RECRUITING Phase 1

Human Models of Selective Insulin Resistance: Pancreatic Clamp

NCT06558422

NOT YET RECRUITING

Evaluation of Three Pulp Vitality Tests

NCT02636504

NOT YET RECRUITING NA

HIV/STI/HCV Testing and Overdose Prevention Among Survivors of Sex Trafficking

NCT07264582

NOT YET RECRUITING Phase 3

Migraine Headaches Elimination With Patent Foramen Ovale-Directed Therapy

NCT07629635

NOT YET RECRUITING Phase 3

Morphine or Ketamine for Analgesia

NCT06835504

NOT YET RECRUITING NA

Conservative Versus Operative - First Time Shoulder Dislocations

NCT05532150

NOT YET RECRUITING NA

Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing

NCT05532189

NOT YET RECRUITING NA

Conservative Versus Operative - First Time Patella Dislocations

NCT05533671

NOT YET RECRUITING NA

Adaptive Recruitment Curve Analysis Using Bayesian Modeling

NCT07561372

NOT YET RECRUITING NA

Music Intervention for Preterm Birth

NCT05945264

NOT YET RECRUITING NA

Know Your Pressures NYC

NCT05992415

NOT YET RECRUITING Phase 4

Post-op Prednisone and Glucose Monitoring in TKA

NCT07630896

NOT YET RECRUITING NA

Bilevel Positive Airway Pressure (BPAP) for Severe Asthma

NCT07582211

NOT YET RECRUITING Phase 4

Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery

NCT07567495

NOT YET RECRUITING NA

EEG-Guided Analgesic Titration During General Anesthesia to Improve Early Neurocognitive Recovery in Older Patients

NCT04443517

COMPLETED NA

Sleep in Collegiate Baseball Players

NCT07212101

COMPLETED Phase 4

Efficacy of Nanodropper-mediated Topical Anesthetic

NCT06636708

COMPLETED NA

Synbiotic Therapy for NP-PASC

NCT06620406

COMPLETED NA

TechMPower: Advancing HIV/SUD Care and Service Delivery for People in Re-entry

NCT07088770

COMPLETED NA

Text4Vax: Text Message Reminders for Pediatric COVID-19 and Influenza Vaccines 2024-25 Season

NCT06603090

COMPLETED NA

Feasibility of an Oral Intervention for Sexual Health in Transgender Men

NCT06470906

COMPLETED NA

E-mails to Nudge Safer and Better-Informed Prescribing of Risky Drugs

NCT06443385

COMPLETED NA

Probiotic Chocolate Study in Multiple Sclerosis

NCT06475183

COMPLETED NA

Free Time For Wellness Pilot Effectiveness Trial

NCT06474715

COMPLETED NA

Community Health Worker Assisted Task Specific and Cognitive Therapy at Home With Exposure After Stroke

NCT06314308

COMPLETED NA

Data-driven SDM to Reduce Symptom Burden in AF

NCT04993807

TERMINATED

Role of Insulin Action in Psoriasis Pathogenesis

NCT06242847

COMPLETED NA

Using Shared Decision Making to Improve Kidney Transplantation Rates

NCT06141499

COMPLETED NA

Characterizing and Addressing Financial Toxicity in AYAs With Cancer

NCT06072833

COMPLETED NA

Sepsis Electronic Prompting for Timely Intervention and Care for Emergency Department Patients

NCT06117605

COMPLETED NA

Sepsis Electronic Prompting for Timely Intervention and Care for Inpatients

NCT06117618

COMPLETED NA

Messy Memories: Mobile Application Therapy Following Critical Illness

NCT05849454

COMPLETED NA

mLab App Plus: A Randomized Controlled Trial of a Mobile Health (mHealth) Intervention

NCT06059443

COMPLETED NA

Body Electric: a Pragmatic Trial Evaluating the Viability of Movement Breaks

NCT06592209

COMPLETED NA

Restoring Energy With Sub-symptom Threshold Optimized Rehabilitation Exercise for Long COVID

NCT06172803

TERMINATED Phase 1

Siplizumab for Sickle Cell Disease Transplant

NCT06078696

COMPLETED NA

A Digital Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Study

NCT06014177

COMPLETED NA

Nurse Suicide: Physiologic Sleep Health Promotion Trial

NCT06079853

COMPLETED NA

Removing Surrogates' Uncertainty to Reduce Fear and Anxiety After Cardiac Events

NCT06048068

COMPLETED Phase 1

Pancreatic Clamp in NAFLD

NCT05724134

COMPLETED NA

A Skin Glue Versus Subcuticular Suture for Cesarean Closure Study

NCT05903547

COMPLETED NA

Improving Patient Prioritization During Hospital-homecare Transition

NCT04136951

COMPLETED Phase 1

Glycemic Effect of Diazoxide in NAFLD

NCT05729282

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Phase Distribution

PhaseTrial count
Phase 1 86
Phase 2 105
Phase 3 23
Phase 4 65

What is open in the Columbia University pipeline

171 recruiting of 958 indexed (18% open); 597 completed (62%).

Phase mix: 88 late (III/IV) vs 191 early (I/II) (early-phase heavy).

Top condition: Obesity (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Columbia University: open-pipeline peers nationwide

Peers matched on 958 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Columbia UniversityUniversity of MinnesotaBrigham and Women's HospitalHoffmann-La RocheUniversity of California, Los AngelesKite, A Gilead CompanyMirum PharmaceuticalsWest Virginia UniversityHospital for Special Surgery, New York
Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 958 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Columbia University page

958 registered trials is a research-attention snapshot, not an endorsement of Columbia University or any single study.

  • 171 of Columbia University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Columbia University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Columbia University pipeline card: 958 registered trials from official public datasets.Report a data error.