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NCT02602769 · ClinicalTrials.gov registry record
Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome
A clinical trial of Childhood Obesity and Morbid Obesity, sponsored by Columbia University.
- Recruiting
- Registry status
- 12
- Enrollment target
- 2
- Study locations
NCT02602769: Recruiting study of Childhood Obesity and Morbid Obesity, sponsored by Columbia University.
NCT02602769 is a study of Childhood Obesity and Morbid Obesity that is actively recruiting participants, run by Columbia University. The registered enrollment target is 12 participants, below the 560-participant average among 43 other Childhood Obesity trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02602769, a study of Childhood Obesity and Morbid Obesity, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- 12 participants
- Enrollment target
- 2
- Study locations
Study Summary
Rapid onset Obesity, Hypoventilation, Hypothalamic dysfunction and Autonomic Dysregulation (ROHHAD) is a syndrome named in 2007. The hallmark of the syndrome is the rapid onset obesity and dysregulation of central ventilation. There is little information about the metabolic changes that lead to the rapid onset obesity in these children. The investigators would like to study the metabolic phenotype of these children to understand the disturbances in energy balance that lead to the rapid onset obesity.
Primary Outcome
The investigators will perform whole transcriptome profiling of iPSC-derived hypothalamic neurons and compare the whole genome sequencing to identify the changes that may give rise to the disease.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Transcriptome profiling
Study Locations (2)
New York
- Boston Children's Hospital - Boston
- Columbia University Irving Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2015-11 |
| Est. Completion | 2026-12 |
What NCT02602769 shows while recruiting
NCT02602769 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 560-participant average among 43 other Childhood Obesity trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Childhood Obesity appearing as the primary indexed condition, and to 1 intervention - of which Transcriptome profiling is the first listed.
NCT02602769 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT02602769 about?
NCT02602769 is a clinical study titled "Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome". Rapid onset Obesity, Hypoventilation, Hypothalamic dysfunction and Autonomic Dysregulation (ROHHAD) is a syndrome named in 2007. The hallmark of the syndrome is the rapid onset obesity and dysregulation of central ventilation. There is little information about the metabolic changes that lead to the ...
What is the current status of trial NCT02602769?
This trial is currently recruiting. The enrollment target is 12 participants. The study started on 2015-11. Estimated completion is 2026-12.
What conditions does trial NCT02602769 study?
This clinical trial studies the following conditions: Childhood Obesity, Morbid Obesity.
What interventions are being tested in trial NCT02602769?
The interventions under investigation include: Transcriptome profiling (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT02602769?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02602769 being conducted?
This trial has 2 study locations across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02602769's enrollment target sits among peer trials
12 44th of 43 the lowest of 43 other Childhood Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Childhood Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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