Columbia University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Columbia University sits in the top decile of US sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count).

958 total trials 171 currently recruiting 597 completed early-phase tilt top decile by trial count

Columbia University: 958 sponsored US clinical trials, 171 recruiting.

Columbia University sponsors 958 registered US clinical trials on ClinicalTrials.gov, 171 of them currently recruiting, and 597 completed. 88 of these trials are in Phase 3-4 (later-stage) and 191 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 9 trials.

Top-decile sponsor footprint

Columbia University ranks in the top decile of sponsors by registered trial count (#34 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 42/100

597 of 736 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

958 total, page 3 of 20

RECRUITING NA

MyHand-SCI: An Active Hand Orthosis for Spinal Cord Injury

NCT05553457

RECRUITING Phase 1

Vascular Endothelial Dysfunction in Sleep Apnea

NCT05289063

RECRUITING NA

ETE Interventions in the Dental Setting

NCT05584501

RECRUITING NA

Enhanced Nutritional Optimization in LVAD Trial

NCT05655910

RECRUITING NA

Genomic Uniformed-Screening Against Rare Disease In All Newborns

NCT05990179

RECRUITING

Hypoparathyroidism Natural History Study

NCT05793853

RECRUITING Phase 4

Postpartum Hypertension Study

NCT05139238

RECRUITING NA

Breaking up Prolonged Sedentary Behavior to Improve Cardiometabolic Health

NCT05353322

RECRUITING Phase 1

R-MVST Cells for Treatment of Viral Infections

NCT05183490

RECRUITING NA

AVI Didactic Experience for Latinx Patient Treatment Adherence and Non-English Speaker Trial Enrollment Study in Rad Onc

NCT05351424

RECRUITING NA

Pictographs for Preventing Wrong-Patient Errors in NICUs

NCT03960099

RECRUITING NA

Medical Imaging and Thermal Treatment for Breast Tumors Using Harmonic Motion Imaging (HMI)

NCT05219695

RECRUITING NA

Lifestyle Patterns and Glycemic Control

NCT05224986

RECRUITING NA

Stress Phenotypes and Preterm Birth

NCT05229666

RECRUITING

RFA Treatment for Papillary Thyroid Microcarcinoma

NCT05189821

RECRUITING NA

Stick2PrEP Cisgender Women and Trans Individuals

NCT05165745

RECRUITING Phase 1

Using T-Cell Alloreactivity and Chimerism to Guide Immunosuppression Minimization in Intestinal Transplantation

NCT04804891

RECRUITING

Tumor Microenvironment Analysis of Prostate Cancer Metastasis

NCT05304858

RECRUITING Early Phase 1

Spinal Cord Associative Plasticity Study

NCT05163639

RECRUITING NA

StrataCTX® as a Steroid Sparing Device

NCT04087629

RECRUITING

CU-COMMITS: COVID-19 Care in Black and Latino Communities and Households. Clinical and Molecular Outcomes of SARS-CoV-2

NCT05467930

RECRUITING NA

Breast Elasticity Imaging During Neoadjuvant Chemotherapy

NCT04824027

RECRUITING Phase 2

Isatuximab in Patients With Monoclonal Gammopathy of Renal Significance

NCT04614558

RECRUITING Phase 2

Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease

NCT04840979

RECRUITING Phase 2

Photopheresis in Early-stage Mycosis Fungoides

NCT05680558

RECRUITING

How is Social Connection Represented in the Brain?

NCT04577911

RECRUITING

Study of BEST1 Vitelliform Macular Dystrophy

NCT05809635

RECRUITING

Longitudinal Oral Microbiome Sampling for BE

NCT05133102

RECRUITING NA

Brain Research Apprenticeships in New York at Columbia

NCT04728022

RECRUITING

Measuring Physical Activity With ActivPal

NCT06084026

RECRUITING NA

Opioid Dispensing Device for Post-Operative Pain in Cancer Patients

NCT05585788

RECRUITING

Radiofrequency Ablation for BIII Thyroid Nodules

NCT05189808

RECRUITING Phase 2

Tranexamic Acid to Reduce Blood Loss in Spine Surgery

NCT02314988

RECRUITING

ARMOR Study: COVID-19 Seroprevalence Among Healthcare Workers

NCT04367857

RECRUITING

Determinants of SARS (Severe Acute Respiratory Syndrome)-COV2 (COVID-19) Persistence After Convalescence

NCT04448145

RECRUITING NA

Targeted Fortification of Donor Breast Milk in Preterm Infants

NCT04294368

RECRUITING NA

MyHand 2: An Active Hand Orthosis for Stroke Patients

NCT04436042

RECRUITING NA

Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment

NCT03891160

RECRUITING NA

Osteochondral Allograft in the Surgical Treatment of Basal Joint Arthritis

NCT03722537

RECRUITING

RFA of Benign Thyroid Nodules: Clinical Outcomes and Quality of Life Study

NCT05189314

RECRUITING NA

e-Connect: A Service System Intervention for Justice Youth at Risk for Suicide

NCT03586895

RECRUITING Phase 2

Postpartum Low-Dose Aspirin and Preeclampsia

NCT03667326

RECRUITING

Recovery of Consciousness Following Intracerebral Hemorrhage

NCT03990558

RECRUITING

The Impact of Glomerular Disorders on Bone Quality and Strength

NCT04528446

RECRUITING

Autoimmune Features of Neurodegenerative Disorders

NCT04239079

RECRUITING NA

Navio Robotic Versus Conventional Total Knee Arthroplasty

NCT03519269

RECRUITING

CNGB1 and Allied Disorders

NCT04639635

RECRUITING NA

Circadian Misalignment and Energy Balance

NCT03663530

RECRUITING

Amyotrophic Lateral Sclerosis (ALS) Families Project

NCT03865420

RECRUITING NA

Effect of Giving Reduced Fluid in Children After Trauma

NCT04201704

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Phase Distribution

PhaseTrial count
Phase 1 86
Phase 2 105
Phase 3 23
Phase 4 65

What is open in the Columbia University pipeline

171 recruiting of 958 indexed (18% open); 597 completed (62%).

Phase mix: 88 late (III/IV) vs 191 early (I/II) (early-phase heavy).

Top condition: Obesity (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Columbia University: open-pipeline peers nationwide

Peers matched on 958 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Columbia UniversityUniversity of MinnesotaBrigham and Women's HospitalHoffmann-La RocheUniversity of California, Los AngelesKite, A Gilead CompanyMirum PharmaceuticalsWest Virginia UniversityHospital for Special Surgery, New York
Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Columbia University sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 958 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Columbia University page

958 registered trials is a research-attention snapshot, not an endorsement of Columbia University or any single study.

  • 171 of Columbia University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition Columbia University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Columbia University pipeline card: 958 registered trials from official public datasets.Report a data error.