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NCT04676594 · ClinicalTrials.gov registry record
Genentech Validation Tool for Pulmonary Fibrosis
A clinical trial of Interstitial Lung Disease, sponsored by Columbia University.
- Active
- Registry status
- 400
- Enrollment target
- 1
- Study location
NCT04676594: Active study of Interstitial Lung Disease, sponsored by Columbia University.
NCT04676594 is a study of Interstitial Lung Disease that is active but no longer recruiting, run by Columbia University. The registered enrollment target is 400 participants, below the 556-participant average among 36 other Interstitial Lung Disease trials with a reported enrollment target (28% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04676594, a study of Interstitial Lung Disease, is active but no longer recruiting, sponsored by Columbia University.
- ACTIVE NOT RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
Radiology is an important component of the multidisciplinary team. The primary goal of this project will be to create a tool using findings on chest computed tomography (CT) for nearly 300 patients with the most common types of fibrosis. The tool will be tested using chest CT scans of an additional 100 patients with the 3 most common diagnoses of fibrosis. The second objective will be to further validate the tool by performing a reader study with 3 co-investigating radiologists and ask them to look at 100 CT scans of patients with fibrosis without tool and then with tool and see if accuracy of diagnosis improves compared to the working diagnosis when using the tool.
Primary Outcome
Creation of the radiologic diagnostic tool will be identified via statistical analysis of patterns for CT scan features. The patterns will be characterized using latent class analysis (LCA) and the demographic factors that are predictive of each pattern will be identified. Associations between patterns for CT scan features identified using LCA and the disease diagnosis will then be assessed using the Fisher's exact test.
Conditions Studied
Study Locations (1)
New York
- Columbia University Irving Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2020-10-04 |
| Est. Completion | 2026-08 |
What the registry record for NCT04676594 still lists
NCT04676594 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 556-participant average among 36 other Interstitial Lung Disease trials with a reported enrollment target (28% lower).
The record links to 1 condition, with Interstitial Lung Disease appearing as the primary indexed condition, and to 0 interventions.
NCT04676594 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT04676594 about?
NCT04676594 is a clinical study titled "Genentech Validation Tool for Pulmonary Fibrosis". Radiology is an important component of the multidisciplinary team. The primary goal of this project will be to create a tool using findings on chest computed tomography (CT) for nearly 300 patients with the most common types of fibrosis. The tool will be tested using chest CT scans of an additional ...
What is the current status of trial NCT04676594?
This trial is currently active not recruiting. The enrollment target is 400 participants. The study started on 2020-10-04. Estimated completion is 2026-08.
What conditions does trial NCT04676594 study?
This clinical trial studies the following conditions: Interstitial Lung Disease.
Who is sponsoring clinical trial NCT04676594?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04676594 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Interstitial Lung Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04676594's enrollment target sits among peer trials
400 11th of 36 higher than 26 of 36 other Interstitial Lung Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Interstitial Lung Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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