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NCT01532791 · ClinicalTrials.gov registry record
Natural History Study - Mitochondrial Disease
A clinical trial of MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier, sponsored by Columbia University.
- Recruiting
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT01532791: Recruiting study of MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier, sponsored by Columbia University.
NCT01532791 is a study of MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier that is actively recruiting participants, run by Columbia University. The registered enrollment target is 300 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01532791, a study of MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
Carriers of the m.3242A\>G mutation often have clinical symptoms which can include migraines, seizures, strokes, hearing loss, balance issues, gastrointestinal issues, and many other symptoms. The investigators would like to learn more about these disorders and have designed a "Natural History Study" to monitor these conditions over time so that physicians and scientists can not only understand the problems that patients have, but work on developing treatments. The focus of the current work is to evaluate known mutation carriers of the m.3243A\>G (mitochondrial DNA) and their maternal relatives (carrier status not a requirement for participation). Paternal relatives will serve as controls. This study involves no treatment.
Primary Outcome
Evaluate structure and function in brain and muscle
Conditions Studied
Study Locations (1)
New York
- Columbia University - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2004-07 |
| Est. Completion | 2026-07 |
What NCT01532791 shows while recruiting
NCT01532791 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap.
The record links to 1 condition, with MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier appearing as the primary indexed condition, and to 0 interventions.
NCT01532791 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT01532791 about?
NCT01532791 is a clinical study titled "Natural History Study - Mitochondrial Disease". Carriers of the m.3242A\>G mutation often have clinical symptoms which can include migraines, seizures, strokes, hearing loss, balance issues, gastrointestinal issues, and many other symptoms. The investigators would like to learn more about these disorders and have designed a "Natural History Study...
What is the current status of trial NCT01532791?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2004-07. Estimated completion is 2026-07.
What conditions does trial NCT01532791 study?
This clinical trial studies the following conditions: MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier.
Who is sponsoring clinical trial NCT01532791?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01532791 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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