Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05584488 · ClinicalTrials.gov registry record
Allergy and Immunology Natural History Study
A clinical trial of Immune Deficiency and Immune Dysregulation Disorder, sponsored by Columbia University.
- Recruiting
- Registry status
- 10,000
- Enrollment target
- 1
- Study location
NCT05584488: Recruiting study of Immune Deficiency and Immune Dysregulation Disorder, sponsored by Columbia University.
NCT05584488 is a study of Immune Deficiency and Immune Dysregulation Disorder that is actively recruiting participants, run by Columbia University. The registered enrollment target is 10,000 participants, above the 24-participant average among 6 other Immune Deficiency trials with a reported enrollment target (41567% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05584488, a study of Immune Deficiency and Immune Dysregulation Disorder, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- 10,000 participants
- Enrollment target
- 1
- Study location
Study Summary
This protocol is a natural history study designed to evaluate subjects (and some family members) with suspected or identified genetic diseases of allergic inflammation or Immune Dysregulation. Patients determined by clinical history and outside evaluations to be of interest will be consented and enrolled into this study. Blood specimens, stored blood products and derivatives, saliva, hair, fingernail clippings, cord blood, umbilical cord, bone marrow, tissue biopsies and/or buccal swabs from such patients and/or their family members will be obtained for research studies related to understanding genetic and immunopathogenic bases of these diseases. Outside medical records may be obtained, and patient evaluations may be performed to correlate to research laboratory testing results.
Primary Outcome
The primary endpoint will be the determination of the underlying susceptibility trait(s).
Conditions Studied
Study Locations (1)
New York
- Columbia University Irving Medical Center / NewYork-Presbyterian Hospital - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10,000 participants |
| Start Date | 2010-07-16 |
| Est. Completion | 2027-01 |
What NCT05584488 shows while recruiting
NCT05584488 is an observational study that tracks outcomes without assigning an intervention. Its 10,000 participants enrollment target places it among the larger protocols in the corpus, above the 24-participant average among 6 other Immune Deficiency trials with a reported enrollment target (41567% higher).
The record links to 3 conditions, with Immune Deficiency appearing as the primary indexed condition, and to 0 interventions.
NCT05584488 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05584488 about?
NCT05584488 is a clinical study titled "Allergy and Immunology Natural History Study". This protocol is a natural history study designed to evaluate subjects (and some family members) with suspected or identified genetic diseases of allergic inflammation or Immune Dysregulation. Patients determined by clinical history and outside evaluations to be of interest will be consented and enr...
What is the current status of trial NCT05584488?
This trial is currently recruiting. The enrollment target is 10,000 participants. The study started on 2010-07-16. Estimated completion is 2027-01.
What conditions does trial NCT05584488 study?
This clinical trial studies the following conditions: Immune Deficiency, Immune Dysregulation Disorder, Allergic Inflammation.
Who is sponsoring clinical trial NCT05584488?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05584488 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Immune Deficiency
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy
RECRUITING · NA
-
X-linked Moesin Associated Immunodeficiency
RECRUITING
-
R-MVST Cells for Treatment of Viral Infections in Children and Young Adults
RECRUITING · Phase 1
-
Adoptive Transfer of Haploidentical NK Cells and N-803
COMPLETED · Phase 1
-
Immunoglobulin G Therapy Dose Optimization
COMPLETED
-
Personalized Immunotherapeutic for Antibiotic-resistant Infection
COMPLETED · Early Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00160771 · 10,000 participants
Biomechanics/Motion Analysis Laboratory Data Bank
- NCT00896935 · 10,000 participants
Arizona Cancer Center Biospecimen Repository
- NCT00898235 · 10,000 participants
Collection of Samples and Clinical Data From Patients With Amyloid Diseases
- NCT00992303 · 10,000 participants
Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI