Children's Oncology Group

342 total trials 33 currently recruiting 260 completed

Children's Oncology Group sponsors 342 registered US clinical trials on ClinicalTrials.gov, 33 of them currently recruiting, and 260 completed. 103 of these trials are in Phase 3-4 (later-stage) and 128 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Leukemia, with 12 trials.

Trial Pipeline

342 total, page 7 of 7

COMPLETED

Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma

NCT00919269

COMPLETED Phase 2

Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia

NCT00003783

COMPLETED Phase 3

Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver Cancer

NCT00003994

COMPLETED Phase 3

Antibiotic Therapy With or Without G-CSF in Treating Children With Neutropenia and Fever Caused by Chemotherapy

NCT00003739

COMPLETED Phase 2

Chemotherapy in Treating Children With Relapsed Acute Leukemia, Acute Myeloid Leukemia, or Blastic Phase Chronic Myelogenous Leukemia

NCT00003735

COMPLETED Phase 2

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia

NCT00003671

COMPLETED

Genetic Study of Children With Soft Tissue Sarcoma or Rhabdomyosarcoma

NCT00003793

COMPLETED Phase 1

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma

NCT00003625

COMPLETED Phase 2

Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma

NCT00003573

COMPLETED Phase 1

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

NCT00003597

COMPLETED Phase 2

Vinorelbine in Treating Children With Recurrent or Refractory Cancers

NCT00003234

COMPLETED Phase 2

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Hodgkin's or Non-Hodgkin's Lymphoma

NCT00002941

COMPLETED Phase 3

Surgery in Treating Children With Neuroblastoma

NCT00003119

COMPLETED Phase 2

Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors

NCT00003203

COMPLETED Phase 1

Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors

NCT00003141

COMPLETED Phase 1

Combination Chemotherapy in Treating Children With Stage III or Stage IV Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia

NCT00003217

COMPLETED Phase 1

Interleukin-2 in Treating Children Who Have Undergone Bone Marrow Transplantation for Acute Myeloid Leukemia

NCT00009698

COMPLETED Phase 2

Chemotherapy in Treating Children With Recurrent Acute Myeloid Leukemia

NCT00003178

COMPLETED Phase 2

Vinblastine and Methotrexate in Treating Children With Desmoid Tumors

NCT00003019

COMPLETED Phase 2

Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT00002805

COMPLETED Phase 3

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

NCT00002995

COMPLETED Phase 3

Combination Chemotherapy in Treating Children With Progressive Brain Tumors

NCT00002944

COMPLETED Phase 3

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

NCT00005578

COMPLETED

Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain Tumors

NCT00003096

COMPLETED Phase 3

Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma

NCT00002875

COMPLETED Phase 3

Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia

NCT00002816

COMPLETED Phase 3

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

NCT00002827

COMPLETED Phase 3

Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia

NCT00002812

COMPLETED Phase 2

Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Children With Advanced Soft Tissue Sarcoma

NCT00002804

COMPLETED Phase 2

Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia

NCT00002785

COMPLETED Phase 2

Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia

NCT00002756

COMPLETED Phase 1

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Followed by Surgery and/or Radiation Therapy in Treating Young Patients With Advanced Neuroblastoma

NCT00002740

COMPLETED Phase 3

Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia

NCT00002744

COMPLETED Phase 3

Chemotherapy With or Without Surgery, Radiation Therapy, or Stem Cell Transplantation in Treating Young Patients With Kidney Tumors

NCT00002610

COMPLETED Phase 3

Combination Chemotherapy Alone or With Radiation Therapy in Treating Children With Kidney Cancer

NCT00002611

COMPLETED

Detection of Residual Disease in Children Receiving Therapy for Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT00003790

COMPLETED Phase 2

Interferon Alfa in Treating Children With HIV-Related Cancer

NCT00002621

COMPLETED Phase 3

Combination Chemotherapy in Treating Pediatric Patients With Advanced-Stage Large Cell Lymphoma

NCT00002618

COMPLETED Phase 2

Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors

NCT00002594

COMPLETED Phase 2

Combination Chemotherapy in Treating Children With Lymphoma

NCT00002590

COMPLETED

Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer

NCT00002485

COMPLETED Phase 3

Combination Chemotherapy in Treating Children With Neuroblastoma

NCT00003093

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What the Pipeline for Children's Oncology Group Shows

According to the ClinicalTrials.gov registry, Children's Oncology Group is linked to 342 US clinical trials across every stage of research activity. Of those, 33 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 260 are already marked complete, representing roughly 76% of the total.

The phase mix for Children's Oncology Group reports 103 late-stage studies (Phase 3 and Phase 4 combined) and 128 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Children's Oncology Group is Leukemia with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.