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NCT00002875 · ClinicalTrials.gov registry record · Phase 3
Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma
A Phase 3 study, sponsored by Children's Oncology Group.
- Completed
- Registry status
- Phase 3
- Development phase
- 421
- Enrollment target
NCT00002875: Completed Phase 3 study, sponsored by Children's Oncology Group.
NCT00002875 is a Phase 3 study that has completed, run by Children's Oncology Group. The registered enrollment target is 421 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (45% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00002875, a Phase 3 study, has completed, sponsored by Children's Oncology Group.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 421 participants
- Enrollment target
Study Summary
RATIONALE: Radiation therapy uses high energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective when combined with radiation therapy for treating medulloblastoma. PURPOSE: Randomized phase III trial to compare two combination chemotherapy treatments plus radiation therapy in treating children with newly diagnosed medulloblastoma.
Interventions
- DRUG cisplatin
- DRUG cyclophosphamide
- BIOLOGICAL filgrastim
- DRUG mesna
- DRUG lomustine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 421 participants |
| Start Date | 1996-12 |
| Est. Completion | 2011-01 |
| Phase | Phase 3 |
What the finished NCT00002875 record still lists
NCT00002875 is an interventional study that assigns participants to a tested intervention. The registered 421 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (45% lower).
The record links to 0 conditions, and to 5 interventions - of which cisplatin is the first listed.
NCT00002875 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00002875 about?
NCT00002875 is a clinical study titled "Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma". RATIONALE: Radiation therapy uses high energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. It is not yet known which chemotherapy reg...
What is the current status of trial NCT00002875?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 421 participants. The study started on 1996-12. Estimated completion is 2011-01.
What interventions are being tested in trial NCT00002875?
The interventions under investigation include: cisplatin (DRUG), cyclophosphamide (DRUG), filgrastim (BIOLOGICAL), mesna (DRUG), lomustine (DRUG).
Who is sponsoring clinical trial NCT00002875?
This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00002875's enrollment target sits among peer trials
421 890th of 2000 higher than 1,110 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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