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NCT00002756 · ClinicalTrials.gov registry record · Phase 2
Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia
A Phase 2 study of Leukemia, sponsored by Children's Oncology Group.
- Completed
- Registry status
- Phase 2
- Development phase
- 221
- Enrollment target
- 20
- Study locations
NCT00002756: Completed Phase 2 study of Leukemia, sponsored by Children's Oncology Group.
NCT00002756 is a Phase 2 study of Leukemia that has completed, run by Children's Oncology Group. The registered enrollment target is 221 participants, below the 486-participant average among 233 other Leukemia trials with a reported enrollment target (55% lower). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00002756, a Phase 2 study of Leukemia, has completed, sponsored by Children's Oncology Group.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 221 participants
- Enrollment target
- 20
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one chemotherapy drug and giving them as induction intensification may kill more cancer cells. PURPOSE: This phase II trial is studying how well induction intensification works in treating infants with newly diagnosed acute lymphocytic leukemia.
Conditions Studied
Interventions
- DRUG cyclophosphamide
- BIOLOGICAL filgrastim
- DRUG cytarabine
- DRUG asparaginase
- DRUG daunorubicin hydrochloride
Study Locations (20)
California
- Southern California Permanente Medical Group - Downey
- Loma Linda University Cancer Institute at Loma Linda University Medical Center - Loma Linda
- Jonathan Jaques Children's Cancer Center at Miller Children's Hospital - Long Beach
- Children's Hospital Central California - Madera
- Children's Hospital and Research Center - Oakland - Oakland
- Children's Hospital of Orange County - Orange
- Sutter Cancer Center - Sacramento
- Kaiser Permanente Medical Center - Oakland - Sacramento
- Children's Hospital and Health Center - San Diego - San Diego
- UCSF Comprehensive Cancer Center - San Francisco
- Santa Barbara Cottage Children's Hospital - Santa Barbara
- Stanford Cancer Center at Stanford University Medical Center - Stanford
Connecticut
- Carole and Ray Neag Comprehensive Cancer Center at the University of Connecticut Health Center - Farmington
- Yale Cancer Center - New Haven
Florida
- Broward General Medical Center Cancer Center - Fort Lauderdale
- Lee Cancer Care of Lee Memorial Health System - Fort Myers
Alabama
- Comprehensive Cancer Center at University of Alabama at Birmingham - Birmingham
Arizona
- Phoenix Children's Hospital - Phoenix
Arkansas
- Arkansas Cancer Research Center at University of Arkansas for Medical Sciences - Little Rock
District of Columbia
- Children's National Medical Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 221 participants |
| Start Date | 1996-06 |
| Est. Completion | 2012-03 |
| Phase | Phase 2 |
What the finished NCT00002756 record still lists
NCT00002756 is an interventional study that assigns participants to a tested intervention. The registered 221 participants enrollment target is mid-sized for trials with a published cap, below the 486-participant average among 233 other Leukemia trials with a reported enrollment target (55% lower).
The record links to 1 condition, with Leukemia appearing as the primary indexed condition, and to 5 interventions - of which cyclophosphamide is the first listed.
NCT00002756 names 20 study sites across 7 states, led by California, Connecticut, Florida.
Frequently Asked Questions
What is clinical trial NCT00002756 about?
NCT00002756 is a clinical study titled "Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia". RATIONALE: Drugs used in chemotherapy work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one chemotherapy drug and giving them as induction intensification may kill more cancer cells. PURPOSE: This phase II trial is studying how well induction...
What is the current status of trial NCT00002756?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 221 participants. The study started on 1996-06. Estimated completion is 2012-03.
What conditions does trial NCT00002756 study?
This clinical trial studies the following conditions: Leukemia.
What interventions are being tested in trial NCT00002756?
The interventions under investigation include: cyclophosphamide (DRUG), filgrastim (BIOLOGICAL), cytarabine (DRUG), asparaginase (DRUG), daunorubicin hydrochloride (DRUG).
Who is sponsoring clinical trial NCT00002756?
This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00002756 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Leukemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00002756's enrollment target sits among peer trials
221 39th of 233 higher than 195 of 233 other Leukemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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