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NCT00002995 · ClinicalTrials.gov registry record · Phase 3

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

A Phase 3 study, sponsored by Children's Oncology Group.

Completed
Registry status
Phase 3
Development phase
483
Enrollment target

NCT00002995 is a Phase 3 study that has completed, run by Children's Oncology Group. The registered enrollment target is 483 participants.

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The verdict

NCT00002995, a Phase 3 study, has completed, sponsored by Children's Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
483 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether chemotherapy is more effective with or without radiation therapy in treating patients who have rhabdomyosarcoma. PURPOSE: Phase III trial to compare the effectiveness of chemotherapy with or without radiation therapy in treating patients who have newly-diagnosed rhabdomyosarcoma.

Interventions

  • DRUG cyclophosphamide
  • BIOLOGICAL filgrastim
  • BIOLOGICAL sargramostim
  • BIOLOGICAL dactinomycin
  • DRUG vincristine sulfate

Trial Details

FieldValue
Enrollment Target 483 participants
Start Date 1997-08
Est. Completion 2011-01
Phase Phase 3

Sponsor

Children's Oncology Group

342 total trials

What the Registry Record Tells You About NCT00002995

The ClinicalTrials.gov registry entry for NCT00002995 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 483 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Oncology Group, which has 342 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT00002995 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00002995 about?

NCT00002995 is a clinical study titled "Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma". RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether chemotherapy is more effective with or without radiation therapy in treating patien...

What is the current status of trial NCT00002995?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 483 participants. The study started on 1997-08. Estimated completion is 2011-01.

What interventions are being tested in trial NCT00002995?

The interventions under investigation include: cyclophosphamide (DRUG), filgrastim (BIOLOGICAL), sargramostim (BIOLOGICAL), dactinomycin (BIOLOGICAL), vincristine sulfate (DRUG).

Who is sponsoring clinical trial NCT00002995?

This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.