Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00002816 · ClinicalTrials.gov registry record · Phase 3

Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia

A Phase 3 study, sponsored by Children's Oncology Group.

Completed
Registry status
Phase 3
Development phase
120
Enrollment target

NCT00002816: Completed Phase 3 study, sponsored by Children's Oncology Group.

NCT00002816 is a Phase 3 study that has completed, run by Children's Oncology Group. The registered enrollment target is 120 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (84% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00002816, a Phase 3 study, has completed, sponsored by Children's Oncology Group.

COMPLETED
Registry status
Phase 3
Development phase
120 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase III trial to compare the effectiveness of combination chemotherapy in treating children who have relapsed acute lymphoblastic leukemia.

Primary Outcome

The evaluation of the relationship between prognostic or treatment factors and EFS

Interventions

  • DRUG dexamethasone
  • DRUG etoposide
  • DRUG ifosfamide
  • DRUG cytarabine
  • DRUG idarubicin

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 1996-12
Est. Completion 2006-04
Phase Phase 3
Children's Oncology Group

342 total trials

What the finished NCT00002816 record still lists

NCT00002816 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (84% lower).

The record links to 0 conditions, and to 5 interventions - of which dexamethasone is the first listed.

NCT00002816 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002816 about?

NCT00002816 is a clinical study titled "Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia". RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase III trial to compare the effectiveness of combination chemotherapy in treating children who have relapsed acute lymphoblastic leukemia.

What is the current status of trial NCT00002816?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 120 participants. The study started on 1996-12. Estimated completion is 2006-04.

What interventions are being tested in trial NCT00002816?

The interventions under investigation include: dexamethasone (DRUG), etoposide (DRUG), ifosfamide (DRUG), cytarabine (DRUG), idarubicin (DRUG).

Who is sponsoring clinical trial NCT00002816?

This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002816's enrollment target sits among peer trials

120 1619th of 2000 higher than 361 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01174108 · 120 participants · Phase 2

    Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

  • NCT01627301 · 120 participants · NA

    Sympathetic Overactivity in Post-traumatic Stress Disorder

  • NCT02025023 · 120 participants · Phase 3

    Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

  • NCT02128906 · 120 participants · Phase 2

    Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00002816, the US trial registry maintained by the National Library of Medicine. NCT00002816 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.