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NCT00003019 · ClinicalTrials.gov registry record · Phase 2
Vinblastine and Methotrexate in Treating Children With Desmoid Tumors
A Phase 2 study, sponsored by Children's Oncology Group.
- Completed
- Registry status
- Phase 2
- Development phase
- 28
- Enrollment target
NCT00003019: Completed Phase 2 study, sponsored by Children's Oncology Group.
NCT00003019 is a Phase 2 study that has completed, run by Children's Oncology Group. The registered enrollment target is 28 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (79% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00003019, a Phase 2 study, has completed, sponsored by Children's Oncology Group.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 28 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with vinblastine and methotrexate in treating children who have desmoid tumors that are recurrent or untreatable with surgery or radiation therapy.
Primary Outcome
To estimate the efficacy and toxicity of vinblastine and methotrexate for desmoid tumor in children with newly diagnosed or recurrent desmoid tumor who are not good candidates for treatment with surgery or radiation therapy.
Interventions
- DRUG methotrexate
- DRUG vinblastine sulfate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 1997-08 |
| Est. Completion | 2006-09 |
| Phase | Phase 2 |
What the finished NCT00003019 record still lists
NCT00003019 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (79% lower).
The record links to 0 conditions, and to 2 interventions - of which methotrexate is the first listed.
NCT00003019 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00003019 about?
NCT00003019 is a clinical study titled "Vinblastine and Methotrexate in Treating Children With Desmoid Tumors". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with vinblastine and methotrexate in treating children w...
What is the current status of trial NCT00003019?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 28 participants. The study started on 1997-08. Estimated completion is 2006-09.
What interventions are being tested in trial NCT00003019?
The interventions under investigation include: methotrexate (DRUG), vinblastine sulfate (DRUG).
Who is sponsoring clinical trial NCT00003019?
This trial is sponsored by Children's Oncology Group, which has 342 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00003019's enrollment target sits among peer trials
28 1677th of 2000 higher than 304 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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