Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02990819 · ClinicalTrials.gov registry record · Phase 2
Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies
A Phase 2 study of Immunodeficiencies and Immune Dysregulation Syndromes, sponsored by Children's Hospital of Philadelphia.
- Active
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT02990819 is a Phase 2 study of Immunodeficiencies and Immune Dysregulation Syndromes that is active but no longer recruiting, run by Children's Hospital of Philadelphia. The registered enrollment target is 60 participants, below the 375-participant average among 8 other Immunodeficiencies trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02990819, a Phase 2 study of Immunodeficiencies and Immune Dysregulation Syndromes, is active but no longer recruiting, sponsored by Children's Hospital of Philadelphia.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a Phase II trial to determine the ability of a reduced intensity conditioning regimen to allow successful engraftment with alpha/beta T and CD19+ depleted peripheral stem cell grafts from unrelated or partially matched related donors. There are two conditioning regimens depending upon patient diagnosis and age.
Conditions Studied
Interventions
- DEVICE Apha/beta T and CD19+ cell depletion using CliniMACS device
Study Locations (1)
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2016-12 |
| Est. Completion | 2027-12 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02990819
The ClinicalTrials.gov registry entry for NCT02990819 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 375-participant average among 8 other Immunodeficiencies trials with a reported enrollment target (84% lower). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Immunodeficiencies appearing as the primary indexed condition, and to 1 intervention - of which Apha/beta T and CD19+ cell depletion using CliniMACS device is the first listed.
NCT02990819 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT02990819 about?
NCT02990819 is a clinical study titled "Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies". This is a Phase II trial to determine the ability of a reduced intensity conditioning regimen to allow successful engraftment with alpha/beta T and CD19+ depleted peripheral stem cell grafts from unrelated or partially matched related donors. There are two conditioning regimens depending upon patien...
What is the current status of trial NCT02990819?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2016-12. Estimated completion is 2027-12.
What conditions does trial NCT02990819 study?
This clinical trial studies the following conditions: Immunodeficiencies, Immune Dysregulation Syndromes.
What interventions are being tested in trial NCT02990819?
The interventions under investigation include: Apha/beta T and CD19+ cell depletion using CliniMACS device (DEVICE).
Who is sponsoring clinical trial NCT02990819?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02990819 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Immunodeficiencies
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders
ACTIVE NOT RECRUITING · Phase 2
-
CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant
COMPLETED · Phase 2
-
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
RECRUITING · NA
-
Expanded Access Protocol Using CD3+/CD19+ Depleted PBSC
RECRUITING · Early Phase 1
-
Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV
RECRUITING
-
Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders
COMPLETED · Phase 1
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.