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NCT03047746 · ClinicalTrials.gov registry record · NA
Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF
A NA study of Paroxysmal Nocturnal Hemoglobinuria and Inherited Bone Marrow Failure Syndromes, sponsored by Children's Hospital of Philadelphia.
- Active
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT03047746 is a NA study of Paroxysmal Nocturnal Hemoglobinuria and Inherited Bone Marrow Failure Syndromes that is active but no longer recruiting, run by Children's Hospital of Philadelphia. The registered enrollment target is 50 participants, below the 261-participant average among 14 other Paroxysmal Nocturnal Hemoglobinuria trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03047746, a NA study of Paroxysmal Nocturnal Hemoglobinuria and Inherited Bone Marrow Failure Syndromes, is active but no longer recruiting, sponsored by Children's Hospital of Philadelphia.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single arm pilot study using TCR alpha/beta+ T cell-depleted peripheral blood stem cells (PBSC) from closely matched unrelated donors or partially matched/haploidentical related donors for hematopoietic stem cell transplant (HSCT) in patients with acquired and inherited bone marrow failure (BMF) syndromes.
Conditions Studied
Interventions
- DEVICE CliniMACs
Study Locations (1)
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2017-02-01 |
| Est. Completion | 2029-05 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03047746
The ClinicalTrials.gov registry entry for NCT03047746 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 261-participant average among 14 other Paroxysmal Nocturnal Hemoglobinuria trials with a reported enrollment target (81% lower). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Paroxysmal Nocturnal Hemoglobinuria appearing as the primary indexed condition, and to 1 intervention - of which CliniMACs is the first listed.
NCT03047746 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT03047746 about?
NCT03047746 is a clinical study titled "Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF". This is a single arm pilot study using TCR alpha/beta+ T cell-depleted peripheral blood stem cells (PBSC) from closely matched unrelated donors or partially matched/haploidentical related donors for hematopoietic stem cell transplant (HSCT) in patients with acquired and inherited bone marrow failure...
What is the current status of trial NCT03047746?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2017-02-01. Estimated completion is 2029-05.
What conditions does trial NCT03047746 study?
This clinical trial studies the following conditions: Paroxysmal Nocturnal Hemoglobinuria, Inherited Bone Marrow Failure Syndromes, Acquired Aplastic Anemia.
What interventions are being tested in trial NCT03047746?
The interventions under investigation include: CliniMACs (DEVICE).
Who is sponsoring clinical trial NCT03047746?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03047746 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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