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NCT02928991 · ClinicalTrials.gov registry record · Early Phase 1
Fludarabine Based RIC for Bone Marrow Failure Syndromes
A Early Phase 1 study of Bone Marrow Failure Syndromes, sponsored by Children's Hospital of Philadelphia.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 25
- Enrollment target
- 1
- Study location
NCT02928991 is a Early Phase 1 study of Bone Marrow Failure Syndromes that is actively recruiting participants, run by Children's Hospital of Philadelphia. The registered enrollment target is 25 participants, below the 615-participant average among 3 other Bone Marrow Failure Syndromes trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02928991, a Early Phase 1 study of Bone Marrow Failure Syndromes, is actively recruiting participants, sponsored by Children's Hospital of Philadelphia.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a pilot study to determine whether fludarabine-based reduced intensity conditioning (RIC) regimens facilitate successful donor engraftment of patients with acquired aplastic anemia (AA) and Inherited bone marrow failure (iBMF) syndromes undergoing Matched related donor bone marrow transplant (MRD-BMT).
Conditions Studied
Interventions
- OTHER MRD-BMT with Fludarabine-based RIC for Acquired AA
- OTHER MRD-BMT with Fludarabine-based RIC for iBMF with trilineage aplasia
- OTHER MRD-BMT with Fludarabine-based RIC for iBMF without trilineage aplasia
Study Locations (1)
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2015-04 |
| Est. Completion | 2027-12 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02928991
The ClinicalTrials.gov registry entry for NCT02928991 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 615-participant average among 3 other Bone Marrow Failure Syndromes trials with a reported enrollment target (96% lower). The listed sponsor is Children's Hospital of Philadelphia, which has 431 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Bone Marrow Failure Syndromes appearing as the primary indexed condition, and to 3 interventions - of which MRD-BMT with Fludarabine-based RIC for Acquired AA is the first listed.
NCT02928991 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT02928991 about?
NCT02928991 is a clinical study titled "Fludarabine Based RIC for Bone Marrow Failure Syndromes". This is a pilot study to determine whether fludarabine-based reduced intensity conditioning (RIC) regimens facilitate successful donor engraftment of patients with acquired aplastic anemia (AA) and Inherited bone marrow failure (iBMF) syndromes undergoing Matched related donor bone marrow transplant...
What is the current status of trial NCT02928991?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 25 participants. The study started on 2015-04. Estimated completion is 2027-12.
What conditions does trial NCT02928991 study?
This clinical trial studies the following conditions: Bone Marrow Failure Syndromes.
What interventions are being tested in trial NCT02928991?
The interventions under investigation include: MRD-BMT with Fludarabine-based RIC for Acquired AA (OTHER), MRD-BMT with Fludarabine-based RIC for iBMF with trilineage aplasia (OTHER), MRD-BMT with Fludarabine-based RIC for iBMF without trilineage aplasia (OTHER).
Who is sponsoring clinical trial NCT02928991?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02928991 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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