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NCT02323867 · ClinicalTrials.gov registry record · Phase 2
Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies
A Phase 2 study of Lymphoma and Leukemia, sponsored by Children's Hospital of Philadelphia.
- Active
- Registry status
- Phase 2
- Development phase
- 140
- Enrollment target
- 1
- Study location
NCT02323867: Active Phase 2 study of Lymphoma and Leukemia, sponsored by Children's Hospital of Philadelphia.
NCT02323867 is a Phase 2 study of Lymphoma and Leukemia that is active but no longer recruiting, run by Children's Hospital of Philadelphia. The registered enrollment target is 140 participants, below the 483-participant average among 299 other Lymphoma trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02323867, a Phase 2 study of Lymphoma and Leukemia, is active but no longer recruiting, sponsored by Children's Hospital of Philadelphia.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 140 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single arm pilot study for patients using α/β T cell-depleted peripheral Stem Cell Transplantation (PSCT) in with alternative donor sources with hematologic malignancies receiving alternative donor (unrelated or partially matched related) mobilized peripheral stem cells (PSCs) using the CliniMACS system for T cell depletion plus CD19+ B cell depletion to determine efficacy as determined by engraftment and graft versus host disease (GVHD), and one year leukemia free survival.
Conditions Studied
Interventions
- DEVICE Alpha Beta T cell depletion
Study Locations (1)
Pennsylvania
- The Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2014-10 |
| Est. Completion | 2027-10 |
| Phase | Phase 2 |
What the registry record for NCT02323867 still lists
NCT02323867 is an interventional study that assigns participants to a tested intervention. The registered 140 participants enrollment target is mid-sized for trials with a published cap, below the 483-participant average among 299 other Lymphoma trials with a reported enrollment target (71% lower).
The record links to 3 conditions, with Lymphoma appearing as the primary indexed condition, and to 1 intervention - of which Alpha Beta T cell depletion is the first listed.
NCT02323867 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT02323867 about?
NCT02323867 is a clinical study titled "Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies". This is a single arm pilot study for patients using α/β T cell-depleted peripheral Stem Cell Transplantation (PSCT) in with alternative donor sources with hematologic malignancies receiving alternative donor (unrelated or partially matched related) mobilized peripheral stem cells (PSCs) using the Cl...
What is the current status of trial NCT02323867?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 140 participants. The study started on 2014-10. Estimated completion is 2027-10.
What conditions does trial NCT02323867 study?
This clinical trial studies the following conditions: Lymphoma, Leukemia, Myelodysplasia.
What interventions are being tested in trial NCT02323867?
The interventions under investigation include: Alpha Beta T cell depletion (DEVICE).
Who is sponsoring clinical trial NCT02323867?
This trial is sponsored by Children's Hospital of Philadelphia, which has 431 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02323867 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lymphoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02323867's enrollment target sits among peer trials
140 63rd of 299 higher than 237 of 299 other Lymphoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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