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RECRUITING

The Myelin Disorders Biorepository Project

NCT03047369 · View on ClinicalTrials.gov ↗

Study Summary

The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects. The MDBP is one of the world's largest leukodystrophy biorepositories, having enrolled nearly 2,000 affected individuals since it was launched over a decade ago. Researchers working in the biorepository hope to use these materials to uncover new genetic etiologies for various leukodystrophies, develop biomarkers for use in future clinical trials, and better understand the natural history of these disorders. The knowledge gained from these efforts may help improve the diagnostic tools and treatment options available to patients in the future.

Study Locations (20)

California

  • Children's Hospital of Los Angeles — Los Angeles
  • Children's Hospital of Orange County — Orange
  • Stanford University (Lucile Packard Children's Hospital) — Palo Alto
  • University of California, Davis (UC Davis Health) — Sacramento
  • University of California, San Diego (Rady Children's Hospital) — San Diego
  • UCSF Benioff Children's Hospital — San Francisco

Pennsylvania

  • The Children's Hospital of Philadelphia — Philadelphia
  • University of Pennsylvania — Philadelphia
  • University of Pittsburgh Medical Center — Pittsburgh

Minnesota

  • University of Minnesota — Minneapolis
  • Mayo Clinic — Rochester

Ohio

  • Akron Children's Hospital — Akron
  • Nationwide Children's Hospital — Columbus

District of Columbia

  • Children's National Medical Center — Washington D.C.

Georgia

  • Emory University (Children's Healthcare of Atlanta) — Atlanta

Illinois

  • Ann & Robert H. Lurie Children's Hospital of Chicago — Chicago

Maryland

  • Kennedy Krieger Institute — Baltimore

Trial Details

FieldValue
Enrollment Target 12,000 participants
Start Date 2016-12-08
Est. Completion 2030-12-08

Sponsor

Children's Hospital of Philadelphia

492 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03047369

The ClinicalTrials.gov registry entry for NCT03047369 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 12,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Hospital of Philadelphia, which has 492 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 10 conditions, with Adrenoleukodystrophy appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03047369 reports 20 study locations spanning 11 distinct geographic areas — top geographies include California, Pennsylvania, Minnesota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03047369 about?

NCT03047369 is a clinical study titled "The Myelin Disorders Biorepository Project". The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects. The MDBP is one of the world's largest leukodystrophy biorepositories, having enrolled nearly 2,...

What is the current status of trial NCT03047369?

This trial is currently recruiting. The enrollment target is 12,000 participants. The study started on 2016-12-08. Estimated completion is 2030-12-08.

What conditions does trial NCT03047369 study?

This clinical trial studies the following conditions: Adrenoleukodystrophy, White Matter Disease, Leukodystrophy, ALD (Adrenoleukodystrophy), Leukoencephalopathies. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

Who is sponsoring clinical trial NCT03047369?

This trial is sponsored by Children's Hospital of Philadelphia, which has 492 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03047369 being conducted?

This trial has 20 study locations across California, District of Columbia, Georgia, Illinois, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial