Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05272189 · ClinicalTrials.gov registry record · NA

Project 3 Example: Human-AI Collaboration Tester (HAICT) Exp. 7

A NA study of Decision Making and Computer Aided Diagnosis, sponsored by Brigham and Women's Hospital.

Completed
Registry status
NA
Development phase
12
Enrollment target
1
Study location

NCT05272189: Completed NA study of Decision Making and Computer Aided Diagnosis, sponsored by Brigham and Women's Hospital.

NCT05272189 is a NA study of Decision Making and Computer Aided Diagnosis that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 12 participants, below the 906-participant average among 8 other Decision Making trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05272189, a NA study of Decision Making and Computer Aided Diagnosis, has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
NA
Development phase
12 participants
Enrollment target
1
Study location

Study Summary

The study is one part of a "bundle" of experiments that constitute Project Three of a National Eye Institute grant. Project Three includes a series of experiments that investigate how changing the input from a simulated AI can affect the decisions made by human observers in a two-alternative forced choice task (like the decision to recall a woman for further examination in mammography). HAICT 7, the experiment described here, investigates how changing prevalence affects human performance when AI is used as a Second Reader.

Primary Outcome

D' (d-prime) is the signal detection theory measure of the level of performance on a task. It is computed by calculating the proportion of true positive responses =(true positive trials)/(true positive + false negative trials) = p(TP) and by calculating the proportion of false positive responses =(false positive trials)/(false positive + true negative trials) = p(FP). These values are transformed into 'z-scores' (for example, using NORMSINV in Excel to calculate the inverse of the standard norma

Interventions

  • BEHAVIORAL Simulated Second Reader AI
  • BEHAVIORAL Target Prevalence

Study Locations (1)

Massachusetts

  • Visual Attention Lab / Brigham and Women's Hospital - Boston

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2020-01-01
Est. Completion 2025-11-04
Phase NA
Brigham and Women's Hospital

937 total trials

What the finished NCT05272189 record still lists

NCT05272189 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 906-participant average among 8 other Decision Making trials with a reported enrollment target (99% lower).

The record links to 2 conditions, with Decision Making appearing as the primary indexed condition, and to 2 interventions - of which Simulated Second Reader AI is the first listed.

NCT05272189 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT05272189 about?

NCT05272189 is a clinical study titled "Project 3 Example: Human-AI Collaboration Tester (HAICT) Exp. 7". The study is one part of a "bundle" of experiments that constitute Project Three of a National Eye Institute grant. Project Three includes a series of experiments that investigate how changing the input from a simulated AI can affect the decisions made by human observers in a two-alternative forced ...

What is the current status of trial NCT05272189?

This trial is currently completed. It is a NA study. The enrollment target is 12 participants. The study started on 2020-01-01. Estimated completion is 2025-11-04.

What conditions does trial NCT05272189 study?

This clinical trial studies the following conditions: Decision Making, Computer Aided Diagnosis.

What interventions are being tested in trial NCT05272189?

The interventions under investigation include: Simulated Second Reader AI (BEHAVIORAL), Target Prevalence (BEHAVIORAL).

Who is sponsoring clinical trial NCT05272189?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05272189 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Decision Making

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05272189's enrollment target sits among peer trials

12 9th of 8 the lowest of 8 other Decision Making trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Decision Making trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02602769 · 12 participants

    Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

  • NCT02605421 · 12 participants · Phase 2

    Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

  • NCT02619448 · 12 participants · Early Phase 1

    Concurrent Chemotherapy Plus HFR Radiation Therapy in Inoperable NSCLC

  • NCT03311503 · 12 participants · Phase 1

    Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05272189, the US trial registry maintained by the National Library of Medicine. NCT05272189 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.