Brigham and Women's Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).
Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.
Top-decile sponsor footprint
Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
937 total, page 8 of 19
Digitally Assisted Recovery Coach
NCT05393544
Personalizing Intervention to Reduce Clinical Inertia in the Treatment of Hypertension
NCT04603560
Feasibility of Remote Home Support Coaches (SOCIAL Study)
NCT04772820
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Dihydropyridine Calcium Channel Blockers Versus Hydrochlorothiazide
NCT05125224
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Amiloride vs Triamterene
NCT05125237
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - PDE5
NCT05039086
Medication Adherence Patterns in Rheumatic Diseases: A Behavioral Trial
NCT04776161
People-Powered Medicine (PPM): Rheumatoid Arthritis Non-responders to Biologic Therapies (RANT)
NCT05447182
Prediction of the SEPRA Diabetes Trial in Healthcare Claims Data
NCT05577728
PROJECT 2 EXAMPLE: Feedback X Prevalence Using Dermatology Stimuli
NCT05244122
Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts
NCT04196374
COVID-19 Vaccine Response in Treated MS Patients
NCT05060354
Biomarkers for Circadian Timing in Healthy Adults
NCT03956745
Shared Decision-making on Medical Tests and Care Cascades
NCT04902664
Prediction of the COBRRA AF Anticoagulant Trial in Healthcare Claims Data
NCT05256797
Prediction of the COBRRA VTE Anticoagulant Trial in Healthcare Claims Data
NCT05264168
Levari Exp.20: 2D - Partial Feedback
NCT06355999
Beyond COVID-19: Supporting Resilience With a Trauma-informed Music Composition Program
NCT05727514
MAnnitol for Blood Pressure Stability in HemoDialysis (MAP-HD)
NCT04428372
Cognitive Behavioral Therapy (CBT) Pain Prevention Intervention for Women Undergoing Surgery
NCT06335485
Novel Application of Simulation for Providers to Overcome Decisional Gaps in High-risk Prescribing
NCT04668248
Improving Detection and Early Action for HPV-positive Oropharynx Cancer
NCT04871490
Diabetes Remote Intervention to improVe Use of Evidence-based Medications
NCT06046560
Prediction of Patient Deterioration Using Machine Learning
NCT05045742
Safety of TofAcitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA)-Cancer Endpoints
NCT04798287
Extended-Duration Low-Intensity Apixaban to Prevent Recurrence in High-Risk Patients With Provoked Venous Thromboembolism
NCT04168203
Electronic Tools to Increase Recognition and Improve Primary Care Management for Hypertension in Chronic Kidney Disease
NCT03679247
Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques
NCT04814537
Safety of TofAcitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA)- Cardiovascular Endpoints
NCT04772248
Rural Home Hospital: Proof of Concept
NCT04531280
Lipid Management in Renal Transplant Recipients Using Evolocumab.
NCT04608474
Reinforcement Learning in Diabetes Mellitus Trial
NCT04473326
Symptom-specific TMS Targets for Depression and Anxiety
NCT04604210
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines - (DREAM) Probenecid vs Allopurinol
NCT04746989
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Salbutamol vs Long-acting Muscarinic Antagonists
NCT05457868
A Nurse-led, Advance Care Planning Intervention in the Emergency Department
NCT04730986
Breath Biomarkers for Sleep Loss and Circadian Timing
NCT03980340
Comparison of Vasodilator Response of Inhaled Epoprostenol and Inhaled Nitric Oxide
NCT04231084
Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients
NCT04616456
Vitamin D for COVID-19 Trial
NCT04536298
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Methotrexate vs Hydroxychloroquine
NCT04691505
Mindful Meditation for Epidural Catheter Placement
NCT04687085
Replication of the IMPACT COPD Trial in Healthcare Claims Data
NCT05062304
Replication of the DAPA-CKD (Chronic Kidney Disease) Trial in Healthcare Claims Data
NCT04882813
EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines
NCT04607460
Pharmacological Intervention for Symptomatic Mild Sleep Disordered Breathing
NCT04611750
The Impact of Sublingual Sufentanil on Postoperative Pain and Analgesic Requirements in Spine Surgery Patients
NCT04263909
Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity
NCT04519164
Replication of the D58 Asthma Trial in Healthcare Claims Data
NCT04892732
Replication of the P04334 Asthma Trial in Healthcare Claims Data
NCT04892758
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What is open in the Brigham and Women's Hospital pipeline
145 recruiting of 937 indexed (15% open); 608 completed (65%).
Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).
Top condition: Type 2 Diabetes (13 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Brigham and Women's Hospital: open-pipeline peers nationwide
Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 937 trials (± recruiting share)
- Columbia University · 958 trials · 18% recruiting
- Hoffmann-La Roche · 909 trials · 8% recruiting
- University of Minnesota · 966 trials · 19% recruiting
- University of California, Los Angeles · 897 trials · 18% recruiting
Sponsors near 15% open enrollment (± trial volume)
- Incyte Corporation · 15% recruiting · 239 trials
- Northwestern University · 15% recruiting · 1,209 trials
- Nationwide Children's Hospital · 15% recruiting · 188 trials
- University of Michigan Rogel Cancer Center · 15% recruiting · 292 trials
Related
What to do with this Brigham and Women's Hospital page
937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.
- 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.