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NCT04529863 · ClinicalTrials.gov registry record
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tocilizumab vs Abatacept
A clinical trial of Rheumatoid Arthritis, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- 30,432
- Enrollment target
- 1
- Study location
NCT04529863: Completed study of Rheumatoid Arthritis, sponsored by Brigham and Women's Hospital.
NCT04529863 is a study of Rheumatoid Arthritis that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 30,432 participants, above the 4,536-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (571% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04529863, a study of Rheumatoid Arthritis, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- 30,432 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the same indication.
Primary Outcome
Time to dementia onset, i.e., Alzheimer's disease, vascular dementia, senile, presenile, or unspecified dementia, or dementia in other diseases classified elsewhere. Please refer to uploaded protocol for full definition due to size limitations.
Conditions Studied
Interventions
- DRUG Abatacept
- DRUG Tocilizumab
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30,432 participants |
| Start Date | 2020-08-17 |
| Est. Completion | 2021-08-31 |
What the finished NCT04529863 record still lists
NCT04529863 is an observational study that tracks outcomes without assigning an intervention. Its 30,432 participants enrollment target places it among the larger protocols in the corpus, above the 4,536-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (571% higher).
The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions - of which Abatacept is the first listed.
NCT04529863 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04529863 about?
NCT04529863 is a clinical study titled "Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Tocilizumab vs Abatacept". This study aims to evaluate the comparative risk of dementia/Alzheimer's disease onset between patients treated with medications that target specific metabolic pathways and patients treated with alternative medications for the same indication.
What is the current status of trial NCT04529863?
This trial is currently completed. The enrollment target is 30,432 participants. The study started on 2020-08-17. Estimated completion is 2021-08-31.
What conditions does trial NCT04529863 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis.
What interventions are being tested in trial NCT04529863?
The interventions under investigation include: Abatacept (DRUG), Tocilizumab (DRUG).
Who is sponsoring clinical trial NCT04529863?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04529863 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Rheumatoid Arthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04529863's enrollment target sits among peer trials
30,432 4th of 197 higher than 194 of 197 other Rheumatoid Arthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rheumatoid Arthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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