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NCT07199517 · ClinicalTrials.gov registry record · NA
Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit
A NA study of Tobacco Use and Cigarette Smoking, sponsored by Abramson Cancer Center at Penn Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 472
- Enrollment target
- 1
- Study location
NCT07199517: Recruiting NA study of Tobacco Use and Cigarette Smoking, sponsored by Abramson Cancer Center at Penn Medicine.
NCT07199517 is a NA study of Tobacco Use and Cigarette Smoking that is actively recruiting participants, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 472 participants, above the 373-participant average among 76 other Tobacco Use trials with a reported enrollment target (27% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07199517, a NA study of Tobacco Use and Cigarette Smoking, is actively recruiting participants, sponsored by Abramson Cancer Center at Penn Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 472 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to investigate harm-reduction sampling in a choice format versus medicinal nicotine sampling on smoking behavior, identify mechanisms of sampling's effects, and explore moderators of these effects among a national sample of people unmotivated to quit smoking. Participants will be randomized 2:1 to choose one of three harm-reduction products (ECIG, IQOS, ONP) versus a medicinal nicotine control condition (nicotine patch + lozenge, NPL), receive a 4-week starter product regimen, and then be followed for 6 months to assess use behavior.
Primary Outcome
Seven-day point prevalence smoking abstinence (CO \< 5) will be measured at the 3-month (secondary endpoint) and 6-month follow-up (primary endpoint) via the valid and reliable TLFB procedure and biochemically verified through a CO \< 5 ppm.
Conditions Studied
Interventions
- OTHER HRP Sampling period
- OTHER NPL Sampling period
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 472 participants |
| Start Date | 2026-01-12 |
| Est. Completion | 2030-07 |
| Phase | NA |
What NCT07199517 shows while recruiting
NCT07199517 is an interventional study that assigns participants to a tested intervention. The registered 472 participants enrollment target is mid-sized for trials with a published cap, above the 373-participant average among 76 other Tobacco Use trials with a reported enrollment target (27% higher).
The record links to 3 conditions, with Tobacco Use appearing as the primary indexed condition, and to 2 interventions - of which HRP Sampling period is the first listed.
NCT07199517 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07199517 about?
NCT07199517 is a clinical study titled "Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit". This study aims to investigate harm-reduction sampling in a choice format versus medicinal nicotine sampling on smoking behavior, identify mechanisms of sampling's effects, and explore moderators of these effects among a national sample of people unmotivated to quit smoking. Participants will be ran...
What is the current status of trial NCT07199517?
This trial is currently recruiting. It is a NA study. The enrollment target is 472 participants. The study started on 2026-01-12. Estimated completion is 2030-07.
What conditions does trial NCT07199517 study?
This clinical trial studies the following conditions: Tobacco Use, Cigarette Smoking, Cigarette Smoking Behavior.
What interventions are being tested in trial NCT07199517?
The interventions under investigation include: HRP Sampling period (OTHER), NPL Sampling period (OTHER).
Who is sponsoring clinical trial NCT07199517?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07199517 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tobacco Use
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07199517's enrollment target sits among peer trials
472 13th of 76 higher than 64 of 76 other Tobacco Use trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tobacco Use trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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