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NCT05758688 · ClinicalTrials.gov registry record · Phase 2
PROton Therapy for Post Surgical Treatment of GYNecologic Cancer
A Phase 2 study of Endometrial Cancer and Cervical Cancer, sponsored by Abramson Cancer Center at Penn Medicine.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 25
- Enrollment target
- 3
- Study locations
NCT05758688: Recruiting Phase 2 study of Endometrial Cancer and Cervical Cancer, sponsored by Abramson Cancer Center at Penn Medicine.
NCT05758688 is a Phase 2 study of Endometrial Cancer and Cervical Cancer that is actively recruiting participants, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 25 participants, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (95% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05758688, a Phase 2 study of Endometrial Cancer and Cervical Cancer, is actively recruiting participants, sponsored by Abramson Cancer Center at Penn Medicine.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 25 participants
- Enrollment target
- 3
- Study locations
Study Summary
This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic cancers. The purpose of this study is to estimate rate of acute clinician-reported gastrointestinal (GI) toxicity using WP PBS PRT in the definitive treatment of gynecologic cancers in the post-surgical, adjuvant setting.
Primary Outcome
Determine the rate of acute clinician-reported gastrointestinal (GI), with the Common Terminology Criteria for Adverse Events (CTCAE v5.0) criteria. Acute GI grade 2 or higher toxicity is the primary powering endpoint.
Conditions Studied
Interventions
- RADIATION Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT)
Study Locations (3)
Pennsylvania
- Lancaster General Health - Ann B. Barshinger Cancer Institute - Lancaster
- University of Pennsylvania - Philadelphia
New Jersey
- Virtua Health - Voorhees Township
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2023-11-06 |
| Est. Completion | 2026-11 |
| Phase | Phase 2 |
What NCT05758688 shows while recruiting
NCT05758688 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (95% lower).
The record links to 3 conditions, with Endometrial Cancer appearing as the primary indexed condition, and to 1 intervention - of which Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) is the first listed.
NCT05758688 reports a single indexed study location in Pennsylvania, New Jersey.
Frequently Asked Questions
What is clinical trial NCT05758688 about?
NCT05758688 is a clinical study titled "PROton Therapy for Post Surgical Treatment of GYNecologic Cancer". This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic cancers. The purpose of this study is to estimate rate of acute clinician-rep...
What is the current status of trial NCT05758688?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 25 participants. The study started on 2023-11-06. Estimated completion is 2026-11.
What conditions does trial NCT05758688 study?
This clinical trial studies the following conditions: Endometrial Cancer, Cervical Cancer, Uterine Cancer.
What interventions are being tested in trial NCT05758688?
The interventions under investigation include: Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) (RADIATION).
Who is sponsoring clinical trial NCT05758688?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05758688 being conducted?
This trial has 3 study locations across New Jersey, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05758688's enrollment target sits among peer trials
25 158th of 181 higher than 21 of 181 other Endometrial Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Endometrial Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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