Abramson Cancer Center at Penn Medicine

402 total trials 74 currently recruiting 235 completed

Abramson Cancer Center at Penn Medicine sponsors 402 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 235 completed. 3 of these trials are in Phase 3-4 (later-stage) and 175 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 20 trials.

Trial Pipeline

402 total, page 2 of 9

RECRUITING

Role of the Immune Environment in Response to Therapy in Breast Cancer

NCT05396612

RECRUITING NA

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

NCT05427240

RECRUITING Phase 1

SBRT With Atezo/Bev for HCC

NCT05488522

RECRUITING NA

Comparing Two Ways to Manage Head and Neck Lymphedema

NCT05182229

RECRUITING Phase 2

CAR-T Followed by Bispecific Antibodies

NCT04889716

RECRUITING Phase 2

ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer

NCT04523857

RECRUITING Phase 2

CapTemY90 for Grade 2/3 NET Liver Metastases

NCT04339036

RECRUITING Phase 2

Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer

NCT04841148

RECRUITING

CTNNA1 Familial Expansion Study

NCT05126290

RECRUITING NA

Physiologic MR Imaging of Salivary Gland Tumors

NCT04452162

RECRUITING Phase 2

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

NCT04332367

RECRUITING

Autoimmunity After Checkpoint Blockade

NCT04119713

RECRUITING

Li-Fraumeni Syndrome/TP53 Biobank

NCT04367246

RECRUITING Phase 1

[18F] F-GLN by PET/CT in Breast Cancer

NCT03863457

RECRUITING Phase 1

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

NCT03546829

RECRUITING Phase 2

Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma

NCT03646617

RECRUITING

Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

NCT03680677

RECRUITING NA

PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast Cancer

NCT02732171

RECRUITING Phase 1

Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

NCT02637934

RECRUITING

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

NCT02478892

RECRUITING NA

Ovarian Tissue Transplantation

NCT01870752

RECRUITING

Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples

NCT01985919

RECRUITING

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

NCT02346435

RECRUITING

The Radiation Oncology Registry and Biosample Repository

NCT01577251

ACTIVE NOT RECRUITING NA

Increasing Screening for Cancer Using EHR-Nudges Replication

NCT06995703

ACTIVE NOT RECRUITING

Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian Cancer

NCT06436248

ACTIVE NOT RECRUITING NA

Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening and Enhanced Navigation on Care Delivery for Patients With Breast Cancer

NCT06019988

ACTIVE NOT RECRUITING NA

Lipiodol Deposition Using Endhole vs. Pressure-Modulated Delivery

NCT06204159

ACTIVE NOT RECRUITING NA

Nudge to Gynecologic Oncology

NCT06451263

ACTIVE NOT RECRUITING NA

A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research

NCT05852860

ACTIVE NOT RECRUITING NA

Project Looking-Glass Evaluation

NCT06056063

ACTIVE NOT RECRUITING NA

Penn Medicine Biobank Return of Results Program

NCT06089954

ACTIVE NOT RECRUITING NA

Increasing Adherence to Lung Cancer Screening

NCT05832008

ACTIVE NOT RECRUITING NA

Behavioral Economic Approaches for Population-Based Colorectal Cancer Screening

NCT05693649

ACTIVE NOT RECRUITING NA

The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients

NCT05226078

ACTIVE NOT RECRUITING Phase 2

Shortened Course Adjuvant Radiotherapy Following TORS

NCT05714657

ACTIVE NOT RECRUITING

Vaccine Responses in Cancer

NCT06605625

ACTIVE NOT RECRUITING NA

Understanding Quality of Life Among Patients With Cancer Receiving Palliative Care

NCT05331625

ACTIVE NOT RECRUITING Phase 2

RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy

NCT04827862

ACTIVE NOT RECRUITING NA

Preliminary Investigation of β-hydroxybutyrate Supplementation in Colorectal Cancer Prevention

NCT05338307

ACTIVE NOT RECRUITING Phase 2

XmAb20717 in Advanced Biliary Tract Cancers

NCT05297903

ACTIVE NOT RECRUITING

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer

NCT05096338

ACTIVE NOT RECRUITING

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer

NCT05078190

ACTIVE NOT RECRUITING

Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense Breasts

NCT04854304

ACTIVE NOT RECRUITING NA

Telehealth Weight Loss Program for Breast Cancer Survivors

NCT04855552

ACTIVE NOT RECRUITING NA

Effectiveness of MyCancerGene to Optimize Genetic Testing Outcomes

NCT04774445

ACTIVE NOT RECRUITING Phase 1

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

NCT04367675

ACTIVE NOT RECRUITING NA

Implementation Strategies for Monitoring Adherence in Real Time

NCT04347161

ACTIVE NOT RECRUITING Phase 1

BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy

NCT04454528

ACTIVE NOT RECRUITING

Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy

NCT04305613

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Phase Distribution

PhaseTrial count
Phase 1 113
Phase 2 62
Phase 3 1
Phase 4 2

What the Pipeline for Abramson Cancer Center at Penn Medicine Shows

According to the ClinicalTrials.gov registry, Abramson Cancer Center at Penn Medicine is linked to 402 US clinical trials across every stage of research activity. Of those, 74 studies are currently recruiting, about 18% of the sponsor's indexed portfolio, and 235 are already marked complete, representing roughly 58% of the total.

The phase mix for Abramson Cancer Center at Penn Medicine reports 3 late-stage studies (Phase 3 and Phase 4 combined) and 175 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Abramson Cancer Center at Penn Medicine is Breast Cancer with 20 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.