Abramson Cancer Center at Penn Medicine

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Abramson Cancer Center at Penn Medicine sits in the top decile of US sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count).

402 total trials 74 currently recruiting 235 completed early-phase tilt top decile by trial count

Abramson Cancer Center at Penn Medicine: 402 sponsored US clinical trials, 74 recruiting.

Abramson Cancer Center at Penn Medicine sponsors 402 registered US clinical trials on ClinicalTrials.gov, 74 of them currently recruiting, and 235 completed. 3 of these trials are in Phase 3-4 (later-stage) and 175 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 20 trials.

Top-decile sponsor footprint

Abramson Cancer Center at Penn Medicine ranks in the top decile of sponsors by registered trial count (#92 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 49/100

235 of 280 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

402 total, page 2 of 9

RECRUITING

Role of the Immune Environment in Response to Therapy in Breast Cancer

NCT05396612

RECRUITING NA

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

NCT05427240

RECRUITING Phase 1

SBRT With Atezo/Bev for HCC

NCT05488522

RECRUITING NA

Comparing Two Ways to Manage Head and Neck Lymphedema

NCT05182229

RECRUITING Phase 2

CAR-T Followed by Bispecific Antibodies

NCT04889716

RECRUITING Phase 2

ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer

NCT04523857

RECRUITING Phase 2

CapTemY90 for Grade 2/3 NET Liver Metastases

NCT04339036

RECRUITING Phase 2

Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer

NCT04841148

RECRUITING

CTNNA1 Familial Expansion Study

NCT05126290

RECRUITING NA

Physiologic MR Imaging of Salivary Gland Tumors

NCT04452162

RECRUITING Phase 2

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

NCT04332367

RECRUITING

Autoimmunity After Checkpoint Blockade

NCT04119713

RECRUITING

Li-Fraumeni Syndrome/TP53 Biobank

NCT04367246

RECRUITING Phase 1

[18F] F-GLN by PET/CT in Breast Cancer

NCT03863457

RECRUITING Phase 1

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

NCT03546829

RECRUITING Phase 2

Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma

NCT03646617

RECRUITING

Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

NCT03680677

RECRUITING NA

PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast Cancer

NCT02732171

RECRUITING Phase 1

Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

NCT02637934

RECRUITING

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

NCT02478892

RECRUITING NA

Ovarian Tissue Transplantation

NCT01870752

RECRUITING

Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples

NCT01985919

RECRUITING

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

NCT02346435

RECRUITING

The Radiation Oncology Registry and Biosample Repository

NCT01577251

ACTIVE NOT RECRUITING NA

Increasing Screening for Cancer Using EHR-Nudges Replication

NCT06995703

ACTIVE NOT RECRUITING

Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian Cancer

NCT06436248

ACTIVE NOT RECRUITING NA

Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening and Enhanced Navigation on Care Delivery for Patients With Breast Cancer

NCT06019988

ACTIVE NOT RECRUITING NA

Lipiodol Deposition Using Endhole vs. Pressure-Modulated Delivery

NCT06204159

ACTIVE NOT RECRUITING NA

Nudge to Gynecologic Oncology

NCT06451263

ACTIVE NOT RECRUITING NA

A Patient-Oriented Research Mentoring Program in Tobacco Dependence and Implementation Science Research

NCT05852860

ACTIVE NOT RECRUITING NA

Project Looking-Glass Evaluation

NCT06056063

ACTIVE NOT RECRUITING NA

Penn Medicine Biobank Return of Results Program

NCT06089954

ACTIVE NOT RECRUITING NA

Increasing Adherence to Lung Cancer Screening

NCT05832008

ACTIVE NOT RECRUITING NA

Behavioral Economic Approaches for Population-Based Colorectal Cancer Screening

NCT05693649

ACTIVE NOT RECRUITING NA

The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients

NCT05226078

ACTIVE NOT RECRUITING Phase 2

Shortened Course Adjuvant Radiotherapy Following TORS

NCT05714657

ACTIVE NOT RECRUITING

Vaccine Responses in Cancer

NCT06605625

ACTIVE NOT RECRUITING NA

Understanding Quality of Life Among Patients With Cancer Receiving Palliative Care

NCT05331625

ACTIVE NOT RECRUITING Phase 2

RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy

NCT04827862

ACTIVE NOT RECRUITING NA

Preliminary Investigation of β-hydroxybutyrate Supplementation in Colorectal Cancer Prevention

NCT05338307

ACTIVE NOT RECRUITING Phase 2

XmAb20717 in Advanced Biliary Tract Cancers

NCT05297903

ACTIVE NOT RECRUITING

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer

NCT05096338

ACTIVE NOT RECRUITING

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer

NCT05078190

ACTIVE NOT RECRUITING

Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense Breasts

NCT04854304

ACTIVE NOT RECRUITING NA

Telehealth Weight Loss Program for Breast Cancer Survivors

NCT04855552

ACTIVE NOT RECRUITING NA

Effectiveness of MyCancerGene to Optimize Genetic Testing Outcomes

NCT04774445

ACTIVE NOT RECRUITING Phase 1

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

NCT04367675

ACTIVE NOT RECRUITING NA

Implementation Strategies for Monitoring Adherence in Real Time

NCT04347161

ACTIVE NOT RECRUITING Phase 1

BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy

NCT04454528

ACTIVE NOT RECRUITING

Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy

NCT04305613

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Phase Distribution

PhaseTrial count
Phase 1 113
Phase 2 62
Phase 3 1
Phase 4 2

What is open in the Abramson Cancer Center at Penn Medicine pipeline

74 recruiting of 402 indexed (18% open); 235 completed (58%).

Phase mix: 3 late (III/IV) vs 175 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (20 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Abramson Cancer Center at Penn Medicine: open-pipeline peers nationwide

Peers matched on 402 registered trials and 18% open enrollment, not the therapeutic-area sidebar.

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 02004006008001,000 10%15%20%25% Total trials Recruiting share Abramson Cancer Center at Penn MedicineCase Comprehensive Cancer CenterUniversity of NebraskaTakedaUniversity of Kansas Medical CenterUniversity of Maryland, BaltimoreHenry Ford Health SystemNew York Institute of TechnologyUniversity of California, San Diego
Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Abramson Cancer Center at Penn Medicine sits below the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 402 trials (± recruiting share)

Sponsors near 18% open enrollment (± trial volume)

What to do with this Abramson Cancer Center at Penn Medicine page

402 registered trials is a research-attention snapshot, not an endorsement of Abramson Cancer Center at Penn Medicine or any single study.

  • 74 of Abramson Cancer Center at Penn Medicine's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Abramson Cancer Center at Penn Medicine studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Abramson Cancer Center at Penn Medicine pipeline card: 402 registered trials from official public datasets.Report a data error.