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NCT07478848 · ClinicalTrials.gov registry record · Phase 1
Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas
A Phase 1 study, sponsored by Abramson Cancer Center at Penn Medicine.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 14
- Enrollment target
NCT07478848: Recruiting Phase 1 study, sponsored by Abramson Cancer Center at Penn Medicine.
NCT07478848 is a Phase 1 study that is actively recruiting participants, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 14 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07478848, a Phase 1 study, is actively recruiting participants, sponsored by Abramson Cancer Center at Penn Medicine.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 14 participants
- Enrollment target
Study Summary
This clinical trial assesses whether it is feasible to use radiation therapy with vancomycin prior to CAR T-cell therapy for patients with large B-cell lymphomas
Primary Outcome
rate of CART-related cytokine release syndrome
Interventions
- RADIATION Radiation Therapy
- BIOLOGICAL CAR-T
- DRUG Vancomycin 125mg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2026-05-29 |
| Est. Completion | 2029-01-01 |
| Phase | Phase 1 |
What NCT07478848 shows while recruiting
NCT07478848 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 3 interventions - of which Radiation Therapy is the first listed.
NCT07478848 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07478848 about?
NCT07478848 is a clinical study titled "Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas". This clinical trial assesses whether it is feasible to use radiation therapy with vancomycin prior to CAR T-cell therapy for patients with large B-cell lymphomas
What is the current status of trial NCT07478848?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2026-05-29. Estimated completion is 2029-01-01.
What interventions are being tested in trial NCT07478848?
The interventions under investigation include: Radiation Therapy (RADIATION), CAR-T (BIOLOGICAL), Vancomycin 125mg (DRUG).
Who is sponsoring clinical trial NCT07478848?
This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07478848's enrollment target sits among peer trials
14 1844th of 2000 higher than 154 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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