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NCT06694181 · ClinicalTrials.gov registry record

Safe and Explainable AI

A clinical trial of Breast Cancer and Sepsis, sponsored by Abramson Cancer Center at Penn Medicine.

Recruiting
Registry status
300,000
Enrollment target
1
Study location

NCT06694181: Recruiting study of Breast Cancer and Sepsis, sponsored by Abramson Cancer Center at Penn Medicine.

NCT06694181 is a study of Breast Cancer and Sepsis that is actively recruiting participants, run by Abramson Cancer Center at Penn Medicine. The registered enrollment target is 300,000 participants, above the 2,558-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (11628% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06694181, a study of Breast Cancer and Sepsis, is actively recruiting participants, sponsored by Abramson Cancer Center at Penn Medicine.

RECRUITING
Registry status
300,000 participants
Enrollment target
1
Study location

Study Summary

While current AI technology is suitable for automating some repetitive clinical tasks, technical challenges remain in solving critical and gainful problems in the domains of patient and disease management. The proposed research seeks to address issues in medical AI, such as integrating medical knowledge effectively, making AI recommendations explainable to clinicians, and establishing safety guarantees.

Primary Outcome

Develop and evaluate novel algorithms for training neurosymbolic models. We will develop data- and compute-efficient algorithms for end-to-end training of neurosymbolic models. This task will reduce the burden on clinician experts to provide fine-grained labels on voluminous EHR data.

Interventions

  • OTHER AI-PERSONALIZED CLINICAL DECISION SUPPORT

Study Locations (1)

Pennsylvania

  • Hospital of the University of Pennsylvania - Philadelphia

Trial Details

FieldValue
Enrollment Target 300,000 participants
Start Date 2025-11-29
Est. Completion 2028-11

What NCT06694181 shows while recruiting

NCT06694181 is an observational study that tracks outcomes without assigning an intervention. Its 300,000 participants enrollment target places it among the larger protocols in the corpus, above the 2,558-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (11628% higher).

The record links to 4 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which AI-PERSONALIZED CLINICAL DECISION SUPPORT is the first listed.

NCT06694181 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06694181 about?

NCT06694181 is a clinical study titled "Safe and Explainable AI". While current AI technology is suitable for automating some repetitive clinical tasks, technical challenges remain in solving critical and gainful problems in the domains of patient and disease management. The proposed research seeks to address issues in medical AI, such as integrating medical knowl...

What is the current status of trial NCT06694181?

This trial is currently recruiting. The enrollment target is 300,000 participants. The study started on 2025-11-29. Estimated completion is 2028-11.

What conditions does trial NCT06694181 study?

This clinical trial studies the following conditions: Breast Cancer, Sepsis, Cardiology, Artifical Inteligence.

What interventions are being tested in trial NCT06694181?

The interventions under investigation include: AI-PERSONALIZED CLINICAL DECISION SUPPORT (OTHER).

Who is sponsoring clinical trial NCT06694181?

This trial is sponsored by Abramson Cancer Center at Penn Medicine, which has 402 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06694181 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06694181's enrollment target sits among peer trials

300,000 2nd of 1224 the highest of 1,224 other Breast Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06694181, the US trial registry maintained by the National Library of Medicine. NCT06694181 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.