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NCT05477134 · ClinicalTrials.gov registry record · NA
Arginine Metabolism in Youth With Type 2 Diabetes
A NA study of Type 2 Diabetes, sponsored by Baylor College of Medicine.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT05477134: Recruiting NA study of Type 2 Diabetes, sponsored by Baylor College of Medicine.
NCT05477134 is a NA study of Type 2 Diabetes that is actively recruiting participants, run by Baylor College of Medicine. The registered enrollment target is 30 participants, below the 3,924-participant average among 327 other Type 2 Diabetes trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05477134, a NA study of Type 2 Diabetes, is actively recruiting participants, sponsored by Baylor College of Medicine.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Type 2 diabetes (T2D), once considered only "a disease of older ages," is now a significant public health concern in youth. Although it is characterized by insulin resistance and impaired insulin secretion, its precise etiology and pathogenesis are not yet fully understood. This study aims to (1) explore arginine metabolism in youth with T2D via safe, minimally invasive kinetic experiments using stable isotope tracers and targeted metabolomics, and (2) determine the effect of exogenous arginine administration on β-cell function in youth with T2D, potentially supporting the use of this safe, low-cost, and readily available nutrient to improve pediatric diabetes outcomes.
Primary Outcome
Arginine availability will be assessed and compared between youth with type 2 diabetes and healthy controls.
Conditions Studied
Interventions
- OTHER Stable isotope infusion, oral glucose ingestion, intravenous arginine bolus
Study Locations (1)
Texas
- Texas Children's Hospital / Baylor College of Medicine - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-02-06 |
| Est. Completion | 2027-08-31 |
| Phase | NA |
What NCT05477134 shows while recruiting
NCT05477134 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 3,924-participant average among 327 other Type 2 Diabetes trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Type 2 Diabetes appearing as the primary indexed condition, and to 1 intervention - of which Stable isotope infusion, oral glucose ingestion, intravenous arginine bolus is the first listed.
NCT05477134 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05477134 about?
NCT05477134 is a clinical study titled "Arginine Metabolism in Youth With Type 2 Diabetes". Type 2 diabetes (T2D), once considered only "a disease of older ages," is now a significant public health concern in youth. Although it is characterized by insulin resistance and impaired insulin secretion, its precise etiology and pathogenesis are not yet fully understood. This study aims to (1) ex...
What is the current status of trial NCT05477134?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2023-02-06. Estimated completion is 2027-08-31.
What conditions does trial NCT05477134 study?
This clinical trial studies the following conditions: Type 2 Diabetes.
What interventions are being tested in trial NCT05477134?
The interventions under investigation include: Stable isotope infusion, oral glucose ingestion, intravenous arginine bolus (OTHER).
Who is sponsoring clinical trial NCT05477134?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05477134 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Type 2 Diabetes
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05477134's enrollment target sits among peer trials
30 256th of 327 higher than 57 of 327 other Type 2 Diabetes trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Type 2 Diabetes trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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