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NCT06546085 · ClinicalTrials.gov registry record · NA
Extracellular Vesicles, Insulin Action, and Exercise
A NA study of Obesity and Type 2 Diabetes, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 3
- Study locations
NCT06546085: Recruiting NA study of Obesity and Type 2 Diabetes, sponsored by Rutgers, The State University of New Jersey.
NCT06546085 is a NA study of Obesity and Type 2 Diabetes that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 60 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (93% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06546085, a NA study of Obesity and Type 2 Diabetes, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 3
- Study locations
Study Summary
Extracellular vesicles (EVs) play a role in obesity-induced insulin resistance and likely impact the development of cardiovascular disease. However, little is known on how EVs affect vascular insulin action in people. The purpose of this study is to understand how EVs play a role in type 2 diabetes related cardiovascular disease. This research will also study if exercise can change how EVs impact blood flow and metabolic health. This study will contribute to designing precision medicine to treat/prevent cardiovascular disease in type 2 diabetes.
Primary Outcome
Extracellular vesicles (CD41 -CD31+, CD45, Tx, CD31, CD105) will be isolated from plasma before and during insulin stimulation.
Conditions Studied
Interventions
- BEHAVIORAL Exercise
Study Locations (3)
New Jersey
- Institute for Food, Nutrition, and Health - New Brunswick
- Robert Wood Johnson University Hospital Clinical Research Center - New Brunswick
- Rutgers University Loree Gymnasium - New Brunswick
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-02-10 |
| Est. Completion | 2029-04 |
| Phase | NA |
What NCT06546085 shows while recruiting
NCT06546085 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Exercise is the first listed.
NCT06546085 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT06546085 about?
NCT06546085 is a clinical study titled "Extracellular Vesicles, Insulin Action, and Exercise". Extracellular vesicles (EVs) play a role in obesity-induced insulin resistance and likely impact the development of cardiovascular disease. However, little is known on how EVs affect vascular insulin action in people. The purpose of this study is to understand how EVs play a role in type 2 diabetes ...
What is the current status of trial NCT06546085?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-02-10. Estimated completion is 2029-04.
What conditions does trial NCT06546085 study?
This clinical trial studies the following conditions: Obesity, Type 2 Diabetes.
What interventions are being tested in trial NCT06546085?
The interventions under investigation include: Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT06546085?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06546085 being conducted?
This trial has 3 study locations across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06546085's enrollment target sits among peer trials
60 642nd of 1053 higher than 374 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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