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ClinicalTrials.gov 42 recruiting now official registry

Healthy Participants clinical trials

42 of 120 indexed Healthy Participants trials are currently recruiting.

120 US clinical trials · 42 currently recruiting

Healthy Participants is the subject of 120 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 100 in Phase 1-2 (earlier-stage). The most active sponsor is AstraZeneca, running 18 of these trials.

The research picture

Healthy Participants has 120 registered US clinical trials, 42 of them open to new participants right now, about 35% of the total.

42
recruiting participants now
35%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
18
top sponsor: AstraZeneca
Phase 198Phase 22Phase 31

Active & Recent Trials

120 total, page 1 of 3

RECRUITING Phase 1 400 participants

Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body After a Single Subcutaneous Dose

Amgen

NCT07422285

RECRUITING NA 324 participants

Effect of Limosilactobacillus Reuteri DSM 17648 in Healthy Adults Reporting Upper Gastrointestinal Discomfort

Novozymes A/S

NCT07163637

RECRUITING Phase 1 312 participants

A Study to Assess the Bioequivalence of Trastuzumab Via Different Subcutaneous Delivery Platforms in Healthy Male Participants

Genentech

NCT07214766

RECRUITING Phase 1 310 participants

A Study to Learn About a Vaccine Against E Coli in Healthy Adults

Pfizer

NCT07122986

RECRUITING 200 participants

Sparking Potential, Revealing Infant Neurocognitive Traits

University of Wisconsin, Madison

NCT07390136

RECRUITING Phase 1 176 participants

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants

AstraZeneca

NCT07290283

RECRUITING Phase 1 136 participants

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4954 in Healthy Adult Participants With or Without Elevated Lipoprotein (a) (Lp[a]) Levels, and Participants With Dyslipidemia

AstraZeneca

NCT06980428

RECRUITING NA 120 participants

Effects of PeptiSleep on Sleep Quality in Healthy Adults

Nuritas

NCT07258433

RECRUITING Phase 1 119 participants

FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients

Pfizer

NCT06564389

RECRUITING Phase 3 103 participants

Cognitive Strategies in Early Psychosis 1

University of Minnesota

NCT07231497

RECRUITING Phase 1 100 participants

A Trial to Evaluate the Effect of CD388 on the Immunogenicity of Fluzone® HD Vaccine

Cidara Therapeutics

NCT07300085

RECRUITING 100 participants

Biomarkers Study in Infants With Prior Neonatal Brain Injury

University of Wisconsin, Madison

NCT07413900

RECRUITING NA 100 participants

Cognition and Ultrasound

University of Minnesota

NCT07220655

RECRUITING Phase 1 98 participants

Study of S-892216 Long-acting Injectable (LAI) in Healthy Adult Participants

Shionogi

NCT07093580

RECRUITING Phase 1 96 participants

First-in-human Study of Orally Administered KT-579 in Healthy Adult Participants

Kymera Therapeutics

NCT07412288

RECRUITING Phase 1 75 participants

A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity

AstraZeneca

NCT07013643

RECRUITING Early Phase 1 73 participants

Single and Multiple Ascending Doses of NTX-253 in Healthy Participants and Participants With Stable Schizophrenia

Neurosterix

NCT07344948

RECRUITING Phase 1 72 participants

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of INCA033989 Following Subcutaneous or Intravenous Administration in Healthy Adult Participants

Incyte Corporation

NCT07448155

RECRUITING Phase 1 64 participants

A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years

AstraZeneca

NCT07455825

RECRUITING Phase 1 60 participants

A Food Effect Study to Evaluate the Relative Bioavailability of Nalbuphine Extended-Release Tablets (NAL ER) in Healthy Participants

Trevi Therapeutics

NCT07487740

RECRUITING Early Phase 1 60 participants

Researching Economical Adjuvants to Cancer Therapy

Florida State University

NCT07305259

RECRUITING NA 60 participants

Pistachio Snacking and Metabolic Flexibility

University of South Carolina

NCT07340125

RECRUITING Phase 1 51 participants

A Study to Evaluate the Effect of Food on the Single-Dose Pharmacokinetics and a Drug-Drug Interaction Evaluation of Itraconazole and Carbamazepine on INCB123667 When Administered Orally to Healthy Adult Participants

Incyte Corporation

NCT06909162

RECRUITING Phase 1 48 participants

Comparing the Extent to Which Three Different Formulations of LY4100511 (DC-853) Are Made Available in the Body, Alone and in the Presence of a Drug That Reduces Stomach Acid

Eli Lilly and Company

NCT06916143

RECRUITING NA 40 participants

Fructose Intestinal Gluconeogenesis

Touro University, California

NCT07209202

RECRUITING Phase 1 40 participants

A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics With AZD0780 Following Repeated Dose Administration in Healthy Adults With Elevated LDL-C Levels

AstraZeneca

NCT07423598

RECRUITING NA 40 participants

The Increasing Mindfulness Engagement Project

Florida State University

NCT07170202

RECRUITING 40 participants

CanCan Body Composition Study

Pennington Biomedical Research Center

NCT07305753

RECRUITING NA 38 participants

Royal Ancient Oats™ Study

Standard Process

NCT07371598

RECRUITING Phase 1 32 participants

A Study of Oral E1018 in Healthy Adult Participants

Eisai

NCT06854042

RECRUITING Phase 1 31 participants

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B or Factor VII Deficiency)

Equilibra Bioscience

NCT06349473

RECRUITING Phase 1 30 participants

A Phase 1 Ethnobridging TriaL of AGA2118 in Healthy Japanese, Chinese, and Caucasian ParticipantS (ATLAS)

Angitia Incorporated Limited

NCT07361354

RECRUITING Phase 1 30 participants

Temporal Interference for Thalamocortical Activity and Network Modulation

University of Wisconsin, Madison

NCT07219719

RECRUITING Phase 1 26 participants

A Study to Investigate the Concentrations of Zibotentan and Dapagliflozin in Blood When Given With and Without Food

AstraZeneca

NCT07404137

RECRUITING Early Phase 1 24 participants

First-in-Human Study for the Safety and Evaluation of Two 4R Tau Ligands as Potential PET Radioligands for Imaging Tau Protein in the Brain

Invicro

NCT07348276

RECRUITING NA 24 participants

Glycemic/Insulinemic Effects of Fresh Mango as a Sugar Substitute in Realistic Breakfasts.

Ball State University

NCT07045051

RECRUITING Phase 1 24 participants

A Study to Determine the Safety and Tolerability of AG-236 and How it is Absorbed, Broken Down, and Eliminated From the Body in Healthy Participants

Agios Pharmaceuticals

NCT07075640

RECRUITING Phase 1 20 participants

Impact of Exogenous Ketones on Sleep and Breathing in Healthy Volunteers (K-SLEEP)

Johns Hopkins University

NCT07224074

RECRUITING NA 20 participants

Impact of Supplemental Fiber on Gut and Vascular Health Related in Obesity Phenotypes

Ball State University

NCT07095426

RECRUITING Phase 1 20 participants

A Study of Elenestinib in Healthy Adult Female Participants

Blueprint Medicines Corporation

NCT07388511

RECRUITING Phase 1 15 participants

A Study to Assess Zilucoplan Concentration in Breast Milk of Healthy Lactating Women

UCB Biopharma SRL

NCT06961747

RECRUITING NA 10 participants

Testing a Non-Invasive Spinal Stimulation Device

Gail Forrest

NCT07217314

ACTIVE NOT RECRUITING Phase 2 400 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Occurrence of Anti-Drug Antibodies Following Annual Doses of CD388

Cidara Therapeutics

NCT07225959

ACTIVE NOT RECRUITING Phase 1 132 participants

A Study of LY4060874 in Healthy Participants

Eli Lilly and Company

NCT06709820

ACTIVE NOT RECRUITING Phase 1 104 participants

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD6234 After Repeat Dose Administration in Participants Who Are Overweight or Obese

AstraZeneca

NCT06132841

ACTIVE NOT RECRUITING Phase 1 85 participants

A Phase I Study of CDX-622

Celldex Therapeutics

NCT06650761

ACTIVE NOT RECRUITING NA 60 participants

Effect of Low Volume Sprint Interval Training on Cardiorespiratory Fitness

California State University, San Marcos

NCT07328568

ACTIVE NOT RECRUITING Phase 1 40 participants

A Study of STAR-0310 in Healthy Adult Participants

Astria Therapeutics

NCT06782477

ACTIVE NOT RECRUITING NA 30 participants

Massage: Neuroimaging and Correlates of Response - 1-week Study

University of Utah

NCT07190313

ACTIVE NOT RECRUITING Phase 1 24 participants

A Study of LY4064809 in Healthy Adult Participants

Eli Lilly and Company

NCT07339735

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Phase Distribution

PhaseTrial count
Phase 1 98
Phase 2 2
Phase 3 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Healthy Participants Trial Landscape

120 indexed Healthy Participants studies · 42 recruiting (35%).

Phase mix: 1 late (III/IV) vs 100 early (I/II).

Top sponsor: AstraZeneca (18 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Healthy Participants?

PlainTrial tracks 120 US clinical trials for Healthy Participants, of which 42 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Healthy Participants?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.