Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Surgery: later-stage trial registry
44 of 121 indexed Surgery trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #102 of 28,707 conditions by registered trial count.
121 US clinical trials · 44 currently recruiting · #102 of 28,707 conditions by registered trial count
Surgery: 121 US clinical trials tracked, 44 recruiting.
Surgery is the subject of 121 registered US clinical trials on ClinicalTrials.gov, 44 of them currently open to new participants. 21 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is University of Wisconsin, Madison, running 6 of these trials.
Enrollment posture brief
Registry condition surgery
OPEN 44 | RECR 36% | LATE 21 | EARLY 8 | RANK #102 | SPON 6
Volume-matched condition peers
Nearest open-share peer: Acquired Brain Injury (36% recruiting · 11 trials)
Surgery lists 44 open slots (36% of 121 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Surgery on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Surgery recruits in line with its size-band peers.
44 of 121 indexed trials (36.4%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Surgery trials is spread across many organizations.
University of Wisconsin, Madison accounts for 6 of 121 trials (5%). 77 distinct sponsors appear on at least one study for this condition label.
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Typical Surgery enrolment sits around 100 participants.
Median target enrolment is 100 among the 121 trials that report a genuine target (sentinel values excluded). 60 of those (49.6%) plan for fewer than 100 participants.
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Surgery research is mostly interventional.
96 interventional and 25 observational studies make up this index (79.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
121 total, page 2 of 3
Non-pharmacological Treatment for Pain After Spine Surgery
Dan Rhon
NCT04770480
COgnitive and Physical Exercise to Improve Outcomes After Surgery (COPE-iOS) Study
Vanderbilt University Medical Center
NCT04889417
Effects of Weight Loss Surgery on Bone Health in Adolescents
Massachusetts General Hospital
NCT02557438
Evaluating Outcomes in Cardiac Surgery Patients Who Receive Sugammadex vs. Placebo
Endeavor Health
NCT05801679
Multicenter Phase II Study of Transanal TME (taTME)
Icahn School of Medicine at Mount Sinai
NCT03144765
Metabolomic Profiling of Racial Disparity
Nationwide Children's Hospital
NCT06266429
Permissive Hypotension After Cardiac Surgery
Massachusetts General Hospital
NCT06476613
Regional Anesthesia EMG Study
Nationwide Children's Hospital
NCT06287151
Multimodal Analgesia Effect on Post Surgical Patient
University of California, Davis
NCT04240626
TOF Monitoring Using the TetraGraph in Patients Less Than 1 Year of Age
Joseph D. Tobias
NCT06458023
TetraGraph in Rocuronium Infusions
Joseph D. Tobias
NCT06472284
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
University of Wisconsin, Madison
NCT06184919
Buccal Graft + Collagen Matrix Versus Free Gingival Graft for Keratinized Mucosa Augmentation at Implant Sites
Harvard Medical School (HMS and HSDM)
NCT05844475
RESTORE Declined Livers Study
Washington University School of Medicine
NCT04483102
Circadian Rhythm Disruption in the Hospital Intensive Care Environment
University of Pennsylvania
NCT05828680
Increasing Implementation of Post-Operative Opioid Prescribing Guidelines
University of Pennsylvania
NCT05358522
Multicenter Infection Surveillance Study Following Open Heart Surgery
Halyard Health
NCT00673712
Accuracy of Pulse CO-Oximetry Technology in Characterizing Noninvasive SpHb
University of California, Davis
NCT01997502
Outcomes of Intrathecal Analgesia in Colorectal Surgery
Mayo Clinic
NCT03411109
Redesigning Cardiac Surgery to Reduce Neurologic Injury
Dartmouth-Hitchcock Medical Center
NCT00432536
Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
Bausch & Lomb Incorporated
NCT01591161
ICD-ON Registry: Periop Management of Cardiac Devices
Edward Hospital
NCT02052453
No Opioids PrescrIptions On Discharge After Surgery
Albany Medical College
NCT04469868
Preoperative Chlorhexidine Gluconate (CHG) Cloth on Healthy Subjects
Medline Industries
NCT02222896
Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery
The Cleveland Clinic
NCT05374096
Preoperative Survey to Evaluate Patient Allergy
Nationwide Children's Hospital
NCT05670756
Predictors of Recovery Expectancy
Indiana University
NCT04274491
Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus
University of California, San Francisco
NCT01958320
Study of Recovery of Strength After Surgery Comparing Two Different Medications for Reversal of Muscle Relaxant
Memorial Sloan Kettering Cancer Center
NCT03116997
Opioid Prescribing After Cesarean Delivery
Vanderbilt University Medical Center
NCT03168425
Study Investigating Role of Unalike Patient Positioning on PROMIS Scores
University of Louisville
NCT03446950
Comparison of Ambu Auragain and I-Gel Supraglottic Airways in Adult Patients at an Ambulatory Surgery Center
University of Minnesota
NCT04286581
Management of Antiplatelet Regimen During Surgical Procedures
Baylor Research Institute
NCT03981835
Physical Therapy Following Total Hip Arthroplasty
Orthopedic One
NCT04199390
Foot and Ankle Post-operative Oedema Management Using Geko™
Firstkind
NCT04927234
Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription
Montefiore Medical Center
NCT03588910
Solution Temperature and Fluid Deficit During Hysteroscopy
The University of Texas Health Science Center, Houston
NCT05622097
Prospective Observational Clinical Study to Evaluate Patient Outcomes Following Pharmacogenetic Testing of Patients Undergoing Elective Surgical Procedures
AltheaDx
NCT02605343
Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologic Surgery
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
NCT04117074
Gastric Ultrasound
Alok Moharir
NCT04127331
Feasibility of Obtaining Pulse Oximetry Readings from the Oropharynx
Joseph D. Tobias
NCT05690633
Virtual Phone Visits Compared to In-Person Physical Visits for Post-Operative Follow-Up at a Sports Medicine Clinic
Jonathan Wu
NCT05998148
Single Shot vs Continuous Interscalene Block for Rotator Cuff Repair
University of Chicago
NCT01122745
What is the Impact of the Presence of a Support Person on Informed Consent
Hartford Hospital
NCT03966469
OPTiMASK: Comparison of Pre-oxygenation With Standard Face Mask Combined With High Flow Nasal Oxygen With Pre-oxygenation With Standard Face Mask Alone
Beth Israel Deaconess Medical Center
NCT05495841
Oxygen Reserve Index: Utility as Early Warning for Desaturation in Morbidly Obese Patients
Masimo Corporation
NCT03021551
TAP Versus Thoracic Epidural in Major Abdominal Resections
Corewell Health West
NCT02197988
Pudendal Nerve Block in Vaginal Surgery
MetroHealth Medical Center
NCT04198714
Comparison of Epidural and TAP Block in Abdominal Surgery
University of Nebraska
NCT01848951
NSS-2 BRIDGE Device in Post-Operative Pain Management
Jacques E. Chelly
NCT03555266
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 5 |
| Phase 3 | 9 |
| Phase 4 | 12 |
Top Sponsors
Named interventions
Most-linked intervention names on Surgery records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Surgery trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Surgery page
121 registered trials, 44 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 44 Surgery trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Wisconsin, Madison sponsors the most Surgery trials on record, review their full trial history before evaluating a specific study. See University of Wisconsin, Madison's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Surgery condition card totals 121 registered trials; most-linked intervention NSAID; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.