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NCT05157113 · ClinicalTrials.gov registry record · Phase 4

Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population

A Phase 4 study of Surgery and Cataract, sponsored by University of California, San Francisco.

Recruiting
Registry status
Phase 4
Development phase
70
Enrollment target
1
Study location

NCT05157113: Recruiting Phase 4 study of Surgery and Cataract, sponsored by University of California, San Francisco.

NCT05157113 is a Phase 4 study of Surgery and Cataract that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 70 participants, below the 52,851-participant average among 120 other Surgery trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05157113, a Phase 4 study of Surgery and Cataract, is actively recruiting participants, sponsored by University of California, San Francisco.

RECRUITING
Registry status
Phase 4
Development phase
70 participants
Enrollment target
1
Study location

Study Summary

The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the development of postoperative complications. The investigators propose to replace this complex regimen with a single administration of intraocular antibiotic and subconjunctival steroid at the time of surgery. This pilot study will obtain the preliminary data required to eventually fully evaluate this innovation in postoperative care in a safety-net population with respect to postoperative outcomes, patient compliance, and patient and caregiver satisfaction.

Primary Outcome

Compliance will be reported via a language-specific VOILS DOSE Nonadherence Survey and an in-person verbal/visual adherence check with staff. The survey is separated into two parts: Extent of Nonadherence and Reasons for Nonadherence. Extent of Nonadherence will evaluate whether medicine dosages have been skipped or missed, with a variety of options ranging from "none of the time" to "every time." Reasons for Nonadherence will present possible causes of missed/skipped dosage, with a variety of o

Interventions

  • DRUG Dropless Regimen
  • DRUG Standard Regimen

Study Locations (1)

California

  • Zuckerberg San Francisco General Hospital and Trauma Center (ZSFG) - San Francisco

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2022-05-31
Est. Completion 2026-06-01
Phase Phase 4

What NCT05157113 shows while recruiting

NCT05157113 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 52,851-participant average among 120 other Surgery trials with a reported enrollment target (100% lower).

The record links to 5 conditions, with Surgery appearing as the primary indexed condition, and to 2 interventions - of which Dropless Regimen is the first listed.

NCT05157113 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05157113 about?

NCT05157113 is a clinical study titled "Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population". The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the development of postoperative complications. The investigators propose to replac...

What is the current status of trial NCT05157113?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 70 participants. The study started on 2022-05-31. Estimated completion is 2026-06-01.

What conditions does trial NCT05157113 study?

This clinical trial studies the following conditions: Surgery, Cataract, Satisfaction, Patient, Compliance, Patient, Compliance, Medication.

What interventions are being tested in trial NCT05157113?

The interventions under investigation include: Dropless Regimen (DRUG), Standard Regimen (DRUG).

Who is sponsoring clinical trial NCT05157113?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05157113 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Surgery

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05157113's enrollment target sits among peer trials

70 77th of 120 higher than 44 of 120 other Surgery trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Surgery trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05157113, the US trial registry maintained by the National Library of Medicine. NCT05157113 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.