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NCT05722002 · ClinicalTrials.gov registry record · Phase 4

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

A Phase 4 study of Surgery and Pain, Postoperative, sponsored by University of Michigan.

Recruiting
Registry status
Phase 4
Development phase
900
Enrollment target
8
Study locations

NCT05722002 is a Phase 4 study of Surgery and Pain, Postoperative that is actively recruiting participants, run by University of Michigan. The registered enrollment target is 900 participants, below the 52,844-participant average among 120 other Surgery trials with a reported enrollment target (98% lower). The trial reports 8 study locations across 6 states.

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The verdict

NCT05722002, a Phase 4 study of Surgery and Pain, Postoperative, is actively recruiting participants, sponsored by University of Michigan.

RECRUITING
Registry status
Phase 4
Development phase
900 participants
Enrollment target
8
Study locations

Study Summary

This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll. Eligible participants will be randomized to 1 of 2 groups of medications (Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) plus acetaminophen or low dose opioids plus acetaminophen). It is anticipated that the NSAID group will have superior clinical outcomes and fewer side effects when compared to the opioid group.

Conditions Studied

Surgery Pain, Postoperative

Interventions

  • DRUG Acetaminophen
  • DRUG NSAID
  • DRUG Opioid

Study Locations (8)

Michigan

  • University of Michigan - Ann Arbor
  • Henry Ford Health System - Detroit

Ontario

  • Women's College Hospital - Toronto
  • Unity Health Toronto - Toronto

Missouri

  • Washington University in Saint Louis - St Louis

New Jersey

  • Cooper University Health Care - Camden

North Carolina

  • University of North Carolina Hospitals - Chapel Hill

Pennsylvania

  • Temple University - Temple Health - Philadelphia

Trial Details

FieldValue
Enrollment Target 900 participants
Start Date 2023-02-06
Est. Completion 2026-10
Phase Phase 4

Sponsor

University of Michigan

1,327 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05722002

The ClinicalTrials.gov registry entry for NCT05722002 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 900 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 52,844-participant average among 120 other Surgery trials with a reported enrollment target (98% lower). The listed sponsor is University of Michigan, which has 1,327 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Surgery appearing as the primary indexed condition, and to 3 interventions - of which Acetaminophen is the first listed.

NCT05722002 reports 8 study locations spanning 6 distinct geographic areas - top geographies include Michigan, Ontario, Missouri.

Frequently Asked Questions

What is clinical trial NCT05722002 about?

NCT05722002 is a clinical study titled "Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial". This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll. Eligible participants will be randomized to 1 of 2 groups of medications (Non-Steroidal An...

What is the current status of trial NCT05722002?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 900 participants. The study started on 2023-02-06. Estimated completion is 2026-10.

What conditions does trial NCT05722002 study?

This clinical trial studies the following conditions: Surgery, Pain, Postoperative.

What interventions are being tested in trial NCT05722002?

The interventions under investigation include: Acetaminophen (DRUG), NSAID (DRUG), Opioid (DRUG).

Who is sponsoring clinical trial NCT05722002?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05722002 being conducted?

This trial has 8 study locations across Michigan, Missouri, New Jersey, North Carolina, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.