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ClinicalTrials.gov 108 recruiting now official registry

Spinal Cord Injuries clinical trials

108 of 203 indexed Spinal Cord Injuries trials are currently recruiting.

203 US clinical trials · 108 currently recruiting

Spinal Cord Injuries is the subject of 203 registered US clinical trials on ClinicalTrials.gov, 108 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is University of Louisville, running 9 of these trials.

The research picture

Spinal Cord Injuries has 203 registered US clinical trials, 108 of them open to new participants right now, about 53% of the total.

108
recruiting participants now
53%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
9
top sponsor: University of Louisville
Phase 112Phase 214Phase 32Phase 43

Active & Recent Trials

203 total, page 3 of 5

RECRUITING NA 7 participants

Restoring Motor and Sensory Hand Function in Tetraplegia Using a Neural Bypass System

Chad Bouton

NCT03680872

RECRUITING NA 6 participants

Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury

Georgia Institute of Technology

NCT07128901

RECRUITING NA 6 participants

Cuneiform Nucleus (CnF) Deep Brain Stimulation for Gait Facilitation Following Spinal Cord Injury

University of Miami

NCT07109804

RECRUITING NA 5 participants

The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)

Kessler Foundation

NCT05725499

RECRUITING NA 5 participants

Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury

Medical University of South Carolina

NCT05321017

RECRUITING NA 3 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

Leigh R. Hochberg, MD, PhD.

NCT05724173

RECRUITING NA 2 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)

Leigh R. Hochberg, MD, PhD.

NCT06094205

RECRUITING NA 2 participants

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

Leigh R. Hochberg, MD, PhD.

NCT06511934

ACTIVE NOT RECRUITING NA 200 participants

Scale Up of Project Workout on Wheels Internet Intervention (WOWii)

Craig Hospital

NCT05353842

ACTIVE NOT RECRUITING NA 180 participants

Living Longer and Stronger With Spinal Cord Injury (SCI)

The University of Texas Health Science Center, Houston

NCT06227000

ACTIVE NOT RECRUITING NA 140 participants

Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries

University of South Florida

NCT06233656

ACTIVE NOT RECRUITING NA 121 participants

A Multi-Center Clinical Trial in Individuals With Spinal Cord Injury

Shirley Ryan AbilityLab

NCT03644277

ACTIVE NOT RECRUITING 113 participants

The Impact of Injustice Appraisals on Psychosocial Outcomes Following Spinal Cord Injury: A Longitudinal Study

University of Minnesota

NCT04964362

ACTIVE NOT RECRUITING 75 participants

Qualitative Assessment of the Impact of TTNS on QOL and Participation

Medstar Health Research Institute

NCT04248322

ACTIVE NOT RECRUITING 75 participants

Natural History of Shoulder Pathology in Manual Wheelchair Users

The University of Texas Medical Branch, Galveston

NCT02600910

ACTIVE NOT RECRUITING Phase 2 70 participants

Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury

Spaulding Rehabilitation Hospital

NCT04458324

ACTIVE NOT RECRUITING 70 participants

Nerve Transfer After Spinal Cord Injury- Multi-center

Washington University School of Medicine

NCT04023591

ACTIVE NOT RECRUITING NA 66 participants

Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation

Spaulding Rehabilitation Hospital

NCT05351333

ACTIVE NOT RECRUITING NA 60 participants

Telerehabilitation Early After CNS Injury

TRCare

NCT06069999

ACTIVE NOT RECRUITING NA 60 participants

Home Based Tele-exercise for People With Chronic Neurological Impairments

Burke Medical Research Institute

NCT04564495

ACTIVE NOT RECRUITING Phase 4 40 participants

Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI

James J. Peters Veterans Affairs Medical Center

NCT05101018

ACTIVE NOT RECRUITING Phase 2 40 participants

Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients

Mayo Clinic

NCT04520373

ACTIVE NOT RECRUITING NA 36 participants

Non-Invasive Spinal Cord Stimulation After Injury

University of Louisville

NCT03998527

ACTIVE NOT RECRUITING NA 35 participants

Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCI

Methodist Rehabilitation Center

NCT04029974

ACTIVE NOT RECRUITING NA 32 participants

Transcranial Magnetic Stimulation for Chronic Neuropathic Pain

University of California, San Francisco

NCT05593237

ACTIVE NOT RECRUITING Phase 1 30 participants

Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI

University of Texas Rio Grande Valley

NCT05589402

ACTIVE NOT RECRUITING 30 participants

Design and Delivery Preferences for Exercise Intervention in People With Spinal Cord Injury

University of Alabama at Birmingham

NCT06578780

ACTIVE NOT RECRUITING Phase 2 30 participants

Non-Invasive Stimulation for Improving Motor Function

Kathleen Friel

NCT03592173

ACTIVE NOT RECRUITING NA 30 participants

Transcutaneous Spinal Cord Stimulation to Promote Walking Recovery After Spinal Cord Injury

Craig Hospital

NCT05982171

ACTIVE NOT RECRUITING NA 30 participants

Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury

Spaulding Rehabilitation Hospital

NCT02274116

ACTIVE NOT RECRUITING 25 participants

LTFU Study of Subjects With Cervical SCI Who Received AST-OPC1

Lineage Cell Therapeutics

NCT05975424

ACTIVE NOT RECRUITING NA 24 participants

Targeted HD-tDCS to Improve Upper Limb Rehabilitation in SCI

University of Texas Rio Grande Valley

NCT05589415

ACTIVE NOT RECRUITING NA 24 participants

Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis

Shirley Ryan AbilityLab

NCT02089880

ACTIVE NOT RECRUITING NA 21 participants

Walking Rehabilitation After Spinal Cord Injury: Locomotor Training Using Adaptive Robotics

Brooks Rehabilitation

NCT03504826

ACTIVE NOT RECRUITING NA 20 participants

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

Thomas Jefferson University

NCT04798378

ACTIVE NOT RECRUITING NA 20 participants

Targeted Plasticity Therapy for Upper Limb Rehabilitation in Spinal Cord Injuries

Baylor Research Institute

NCT04288245

ACTIVE NOT RECRUITING NA 16 participants

Standing, Stepping and Voluntary Movement Spinal Cord Epidural Stimulation

Susan Harkema PhD

NCT04123847

ACTIVE NOT RECRUITING Early Phase 1 15 participants

Transformation of Paralysis to Stepping

University of Louisville

NCT04105114

ACTIVE NOT RECRUITING NA 10 participants

SPARC Bladder Mapping and Training Study

University of Louisville

NCT03452007

ACTIVE NOT RECRUITING NA 9 participants

Transcutaneous Spinal Stimulation: Safety and Feasibility for Trunk Control in Children With Spinal Cord Injury

University of Louisville

NCT03975634

ACTIVE NOT RECRUITING Phase 3 6 participants

Neostigmine and Glycopyrrolate by Iontophoresis

James J. Peters Veterans Affairs Medical Center

NCT06351995

ACTIVE NOT RECRUITING 6 participants

Pediatric Locomotor Training Bladder Study

University of Louisville

NCT03559036

ACTIVE NOT RECRUITING NA 6 participants

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

Synchron Medical

NCT05035823

ACTIVE NOT RECRUITING Phase 2 6 participants

Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury

Burke Medical Research Institute

NCT04041063

ACTIVE NOT RECRUITING 5 participants

LTFU Study of Subjects Who Received GRNOPC1

Lineage Cell Therapeutics

NCT05919563

ACTIVE NOT RECRUITING NA 5 participants

Arm and Leg Cycling for Accelerated Recovery From SCI

Shirley Ryan AbilityLab

NCT05619146

ACTIVE NOT RECRUITING NA 4 participants

Grand Valley State University (GVSU) Skills on Wheels

Grand Valley State University

NCT05339932

ACTIVE NOT RECRUITING NA 4 participants

Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain

Prasad Shirvalkar, MD, PhD

NCT03029884

ACTIVE NOT RECRUITING NA 4 participants

Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity

Thomas Jefferson University

NCT05669508

ACTIVE NOT RECRUITING NA 4 participants

Pediatric Powered Wheelchair Standing Devices: An Exploratory Study

Grand Valley State University

NCT05117827

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Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 14
Phase 3 2
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Spinal Cord Injuries Trial Landscape

203 indexed Spinal Cord Injuries studies · 108 recruiting (53%).

Phase mix: 5 late (III/IV) vs 26 early (I/II).

Top sponsor: University of Louisville (9 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Spinal Cord Injuries?

PlainTrial tracks 203 US clinical trials for Spinal Cord Injuries, of which 108 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Spinal Cord Injuries?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.