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Spinal Cord Injuries clinical trials
108 of 203 indexed Spinal Cord Injuries trials are currently recruiting.
203 US clinical trials · 108 currently recruiting
Spinal Cord Injuries is the subject of 203 registered US clinical trials on ClinicalTrials.gov, 108 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 26 in Phase 1-2 (earlier-stage). The most active sponsor is University of Louisville, running 9 of these trials.
The research picture
Spinal Cord Injuries has 203 registered US clinical trials, 108 of them open to new participants right now, about 53% of the total.
- 108
- recruiting participants now
- 53%
- of trials open to enrollment
- 5
- in Phase 3–4 (later-stage)
- 9
- top sponsor: University of Louisville
Active & Recent Trials
203 total, page 3 of 5
Restoring Motor and Sensory Hand Function in Tetraplegia Using a Neural Bypass System
Chad Bouton
NCT03680872
Lower-Limb Exoskeleton Technology for Non-Ambulatory Individuals With Spinal Cord Injury
Georgia Institute of Technology
NCT07128901
Cuneiform Nucleus (CnF) Deep Brain Stimulation for Gait Facilitation Following Spinal Cord Injury
University of Miami
NCT07109804
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
Kessler Foundation
NCT05725499
Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury
Medical University of South Carolina
NCT05321017
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
Leigh R. Hochberg, MD, PhD.
NCT05724173
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)
Leigh R. Hochberg, MD, PhD.
NCT06094205
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)
Leigh R. Hochberg, MD, PhD.
NCT06511934
Scale Up of Project Workout on Wheels Internet Intervention (WOWii)
Craig Hospital
NCT05353842
Living Longer and Stronger With Spinal Cord Injury (SCI)
The University of Texas Health Science Center, Houston
NCT06227000
Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries
University of South Florida
NCT06233656
A Multi-Center Clinical Trial in Individuals With Spinal Cord Injury
Shirley Ryan AbilityLab
NCT03644277
The Impact of Injustice Appraisals on Psychosocial Outcomes Following Spinal Cord Injury: A Longitudinal Study
University of Minnesota
NCT04964362
Qualitative Assessment of the Impact of TTNS on QOL and Participation
Medstar Health Research Institute
NCT04248322
Natural History of Shoulder Pathology in Manual Wheelchair Users
The University of Texas Medical Branch, Galveston
NCT02600910
Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury
Spaulding Rehabilitation Hospital
NCT04458324
Nerve Transfer After Spinal Cord Injury- Multi-center
Washington University School of Medicine
NCT04023591
Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation
Spaulding Rehabilitation Hospital
NCT05351333
Telerehabilitation Early After CNS Injury
TRCare
NCT06069999
Home Based Tele-exercise for People With Chronic Neurological Impairments
Burke Medical Research Institute
NCT04564495
Treatment With Romosozumab Versus Denosumab to Improve Bone Mineral Density and Architecture in Subacute SCI
James J. Peters Veterans Affairs Medical Center
NCT05101018
Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients
Mayo Clinic
NCT04520373
Non-Invasive Spinal Cord Stimulation After Injury
University of Louisville
NCT03998527
Speed of Robotic Leg Movements and Orthostatic Hypotension in Subacute SCI
Methodist Rehabilitation Center
NCT04029974
Transcranial Magnetic Stimulation for Chronic Neuropathic Pain
University of California, San Francisco
NCT05593237
Temporary Inactivation of Strong Muscle Sensation to Improve Rehabilitation Interventions in SCI
University of Texas Rio Grande Valley
NCT05589402
Design and Delivery Preferences for Exercise Intervention in People With Spinal Cord Injury
University of Alabama at Birmingham
NCT06578780
Non-Invasive Stimulation for Improving Motor Function
Kathleen Friel
NCT03592173
Transcutaneous Spinal Cord Stimulation to Promote Walking Recovery After Spinal Cord Injury
Craig Hospital
NCT05982171
Acute Intermittent Hypoxia on Leg Function Following Spinal Cord Injury
Spaulding Rehabilitation Hospital
NCT02274116
LTFU Study of Subjects With Cervical SCI Who Received AST-OPC1
Lineage Cell Therapeutics
NCT05975424
Targeted HD-tDCS to Improve Upper Limb Rehabilitation in SCI
University of Texas Rio Grande Valley
NCT05589415
Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis
Shirley Ryan AbilityLab
NCT02089880
Walking Rehabilitation After Spinal Cord Injury: Locomotor Training Using Adaptive Robotics
Brooks Rehabilitation
NCT03504826
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
Thomas Jefferson University
NCT04798378
Targeted Plasticity Therapy for Upper Limb Rehabilitation in Spinal Cord Injuries
Baylor Research Institute
NCT04288245
Standing, Stepping and Voluntary Movement Spinal Cord Epidural Stimulation
Susan Harkema PhD
NCT04123847
Transformation of Paralysis to Stepping
University of Louisville
NCT04105114
SPARC Bladder Mapping and Training Study
University of Louisville
NCT03452007
Transcutaneous Spinal Stimulation: Safety and Feasibility for Trunk Control in Children With Spinal Cord Injury
University of Louisville
NCT03975634
Neostigmine and Glycopyrrolate by Iontophoresis
James J. Peters Veterans Affairs Medical Center
NCT06351995
Pediatric Locomotor Training Bladder Study
University of Louisville
NCT03559036
COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
Synchron Medical
NCT05035823
Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury
Burke Medical Research Institute
NCT04041063
LTFU Study of Subjects Who Received GRNOPC1
Lineage Cell Therapeutics
NCT05919563
Arm and Leg Cycling for Accelerated Recovery From SCI
Shirley Ryan AbilityLab
NCT05619146
Grand Valley State University (GVSU) Skills on Wheels
Grand Valley State University
NCT05339932
Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
Prasad Shirvalkar, MD, PhD
NCT03029884
Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity
Thomas Jefferson University
NCT05669508
Pediatric Powered Wheelchair Standing Devices: An Exploratory Study
Grand Valley State University
NCT05117827
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 12 |
| Phase 2 | 14 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Spinal Cord Injuries Trial Landscape
203 indexed Spinal Cord Injuries studies · 108 recruiting (53%).
Phase mix: 5 late (III/IV) vs 26 early (I/II).
Top sponsor: University of Louisville (9 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Spinal Cord Injuries?
PlainTrial tracks 203 US clinical trials for Spinal Cord Injuries, of which 108 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Spinal Cord Injuries?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.