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NCT03029884 · ClinicalTrials.gov registry record · NA
Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
A NA study of Chronic Pain and Spinal Cord Injuries, sponsored by Prasad Shirvalkar, MD, PhD.
- Active
- Registry status
- NA
- Development phase
- 4
- Enrollment target
- 1
- Study location
NCT03029884: Active NA study of Chronic Pain and Spinal Cord Injuries, sponsored by Prasad Shirvalkar, MD, PhD.
NCT03029884 is a NA study of Chronic Pain and Spinal Cord Injuries that is active but no longer recruiting, run by Prasad Shirvalkar, MD, PhD. The registered enrollment target is 4 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03029884, a NA study of Chronic Pain and Spinal Cord Injuries, is active but no longer recruiting, sponsored by Prasad Shirvalkar, MD, PhD.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
- 1
- Study location
Study Summary
Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief. A "one-size-fits-all" approach of continuous, 24/7 brain stimulation has helped patients with some movement disorders, but the key to reducing pain may be the activation of stimulation only when needed, as this may help keep the brain from adapting to stimulation effects. By expanding the technological capabilities of an investigative brain stimulation device, the investigators will enable the delivery of stimulation only when pain signals in the brain are high, and then test whether this more personalized stimulation leads to reliable symptom relief for chronic pain patients over extended periods of time.
Primary Outcome
Visual Analog Score is indicated by the patient by marking a 10 cm line as they rate their pain intensity from 0 to 100 in mm. Higher scores represent worse outcome.
Conditions Studied
Interventions
- DEVICE Sham Stimulation
- DEVICE Open-Loop DBS
- DEVICE Closed-Loop DBS
Study Locations (1)
California
- University of California - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2017-10-28 |
| Est. Completion | 2026-06 |
| Phase | NA |
What the registry record for NCT03029884 still lists
NCT03029884 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (99% lower).
The record links to 4 conditions, with Chronic Pain appearing as the primary indexed condition, and to 3 interventions - of which Sham Stimulation is the first listed.
NCT03029884 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT03029884 about?
NCT03029884 is a clinical study titled "Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain". Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief. A "one-size-fits-all" approach of continuous, 24/7 brain stimulation has helped patients with s...
What is the current status of trial NCT03029884?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 4 participants. The study started on 2017-10-28. Estimated completion is 2026-06.
What conditions does trial NCT03029884 study?
This clinical trial studies the following conditions: Chronic Pain, Spinal Cord Injuries, Phantom Limb Pain, Post-Stroke Pain.
What interventions are being tested in trial NCT03029884?
The interventions under investigation include: Sham Stimulation (DEVICE), Open-Loop DBS (DEVICE), Closed-Loop DBS (DEVICE).
Who is sponsoring clinical trial NCT03029884?
This trial is sponsored by Prasad Shirvalkar, MD, PhD, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03029884 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03029884's enrollment target sits among peer trials
4 302nd of 301 the lowest of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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