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NCT05035823 · ClinicalTrials.gov registry record · NA
COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
A NA study of Spinal Cord Injuries and Amyotrophic Lateral Sclerosis, sponsored by Synchron Medical.
- Active
- Registry status
- NA
- Development phase
- 6
- Enrollment target
- 3
- Study locations
NCT05035823: Active NA study of Spinal Cord Injuries and Amyotrophic Lateral Sclerosis, sponsored by Synchron Medical.
NCT05035823 is a NA study of Spinal Cord Injuries and Amyotrophic Lateral Sclerosis that is active but no longer recruiting, run by Synchron Medical. The registered enrollment target is 6 participants, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (90% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05035823, a NA study of Spinal Cord Injuries and Amyotrophic Lateral Sclerosis, is active but no longer recruiting, sponsored by Synchron Medical.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
- 3
- Study locations
Study Summary
The Synchron motor neuroprosthesis (MNP) is intended to be used in subjects with severe motor impairment, unresponsive to medical or rehabilitative therapy and a persistent functioning motor cortex. The purpose of this research is to evaluate safety and feasibility. The MNP is a type of implantable brain computer interface which bypasses dysfunctional motor neurons. The device is designed to restore the transmission of neural signal from the cerebral cortex utilized for neuromuscular control of digital devices, resulting in a successful execution of non-mechanical digital commands.
Primary Outcome
Number of subjects with treatment-related adverse events
Conditions Studied
Interventions
- DEVICE Motor Neuroprosthesis (MNP)
Study Locations (3)
New York
- University at Buffalo Neurosurgery (UBNS) - Buffalo
- Mount Sinai Health System - New York
Pennsylvania
- University of Pittsburgh Medical Center - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2022-04-27 |
| Est. Completion | 2026-09 |
| Phase | NA |
What the registry record for NCT05035823 still lists
NCT05035823 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 62-participant average among 202 other Spinal Cord Injuries trials with a reported enrollment target (90% lower).
The record links to 10 conditions, with Spinal Cord Injuries appearing as the primary indexed condition, and to 1 intervention - of which Motor Neuroprosthesis (MNP) is the first listed.
NCT05035823 reports a single indexed study location in New York, Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT05035823 about?
NCT05035823 is a clinical study titled "COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis". The Synchron motor neuroprosthesis (MNP) is intended to be used in subjects with severe motor impairment, unresponsive to medical or rehabilitative therapy and a persistent functioning motor cortex. The purpose of this research is to evaluate safety and feasibility. The MNP is a type of implantable...
What is the current status of trial NCT05035823?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 6 participants. The study started on 2022-04-27. Estimated completion is 2026-09.
What conditions does trial NCT05035823 study?
This clinical trial studies the following conditions: Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Cervical Spinal Cord Injury, Paralysis.
What interventions are being tested in trial NCT05035823?
The interventions under investigation include: Motor Neuroprosthesis (MNP) (DEVICE).
Who is sponsoring clinical trial NCT05035823?
This trial is sponsored by Synchron Medical, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05035823 being conducted?
This trial has 3 study locations across New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injuries
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05035823's enrollment target sits among peer trials
6 183rd of 202 higher than 14 of 202 other Spinal Cord Injuries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injuries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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